Optimal Embryonic Stage for Transfer in Poor Responders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

300 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-01

Study Completion Date

2022-03-01

Brief Summary

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A Prospective cohort study including couples with poor responder females who undergoing ICSI

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Detailed Description

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Purpose:

To determine the optimal embryonic stage for transfer in poor responders.

Method:

Patients were divided into day 3 transfer group and day 5 transfer group. All cases had the same stimulation protocol and planning to do fresh embryo transfer. Assessments will be at Day 1, Day 3 and Day 5/6 according to Gardner's criteria 1999. Embryological and clinical data were recorded and then analyzed using SPSS (version 23) statistical software.

Conditions

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Poor Response to Ovulation Induction Infertility, Female

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Cleavage stage transfer

Poor responders who transfer their embryos in cleavage stage on day 3

Cleavage stage transfer

Intervention Type OTHER

transferring embryos through ICSI procedures for poor responders on cleavage stage of embryonic development.

Blast stage transfer

Poor responders who transfer their embryos on blast stage on day 5/6

Blast stage transfer

Intervention Type OTHER

transferring embryos through ICSI procedures for poor responders on blast stage of embryonic development.

Interventions

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Cleavage stage transfer

transferring embryos through ICSI procedures for poor responders on cleavage stage of embryonic development.

Intervention Type OTHER

Blast stage transfer

transferring embryos through ICSI procedures for poor responders on blast stage of embryonic development.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* poor responders females with AMH≤ 1.2ng and have ≤ 5 mature oocytes
* couples whose planning to do fresh transfer
* male partners have normal semen parameters according to WHO 2010.