PGTai Results for Embryos Cultured in Sequential Versus Single Step Media

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-12-01

Study Completion Date

2021-06-01

Brief Summary

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A prospective cohort study undergoing ICSI at a private fertility center in Egypt

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Detailed Description

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Purpose:

To evaluate PGTai results for embryos cultured in sequential versus single step media.

Method:

Injected oocytes will divided between Continuous Single Culture-NX media (CSC- NX) with 10% SSS the first group (Irvine, USA) and the other group will be cultured in sequential cleavage and blastocyst media with 10% SPS (SAGE, Denmark).

All blastocytes with 4BB quality and better according to Gardner's criteria 1999 will go through PGTA procedures with PGTai confirmation.

Conditions

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Infertility Aneuploidy Rate Mosaicism

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Evaluating the embryonic development and PGTai results for embryos cultured in sequential media versus single step media.

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Single step media

Embryos cultured in single step media

Group Type ACTIVE_COMPARATOR

Single step media

Intervention Type OTHER

Usage of single step media in embryo culture

Sequential media

Embryos cultured in sequential media

Group Type ACTIVE_COMPARATOR

Sequential media

Intervention Type OTHER

Usage of sequential media in embryo culture

Interventions

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Single step media

Usage of single step media in embryo culture

Intervention Type OTHER

Sequential media

Usage of sequential media in embryo culture

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Female age ≤37 years with ≥ 8 mature oocytes
* Male partner had normal semen parameters according to WHO 2010
* PGT-A was done at the blastocyst stage