Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
200 participants
OBSERVATIONAL
2020-09-01
2027-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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sepsis/septic shock
target population
transcriptomics
transcriptomics
flow-cytometry
peripheral blood myeloid cells and lymphocytes flow-cytometry
cytokines
peripheral blood cytokine analysis
non-septic critically ill
demographically-matched control group
transcriptomics
transcriptomics
flow-cytometry
peripheral blood myeloid cells and lymphocytes flow-cytometry
cytokines
peripheral blood cytokine analysis
healthy control
control group
transcriptomics
transcriptomics
flow-cytometry
peripheral blood myeloid cells and lymphocytes flow-cytometry
cytokines
peripheral blood cytokine analysis
Interventions
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transcriptomics
transcriptomics
flow-cytometry
peripheral blood myeloid cells and lymphocytes flow-cytometry
cytokines
peripheral blood cytokine analysis
Eligibility Criteria
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Inclusion Criteria
* age ≥18
* informed consent
* inclusion within first 24hrs after development/diagnosis of septic shock
Exclusion Criteria
* patients with primary or secondary immunodeficiency
* presence of active haematological malignancy or an active non-haematological malignancy
18 Years
ALL
Yes
Sponsors
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Charles University, Czech Republic
OTHER
Responsible Party
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Thomas Karvunidis
Principal investigator
Principal Investigators
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Thomas Karvunidis, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Carles University Teaching Hospital and Faculty of Medicine in Pilsen, Pilsen, Czech Republic
Locations
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Medical ICU, 1st Dept. of Internal Medicine, Teaching Hospital in Pilsen
Pilsen, Česká Republika, Czechia
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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IMHOTEP
Identifier Type: -
Identifier Source: org_study_id
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