Bio-clinical Evolutive Dynamic in Patients Suffering From Communitary Septic Shock (Biosepsis)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-09-30

Study Completion Date

2012-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Septic shock is a frequent pathology responsible for over 30000 deaths/year in France. Its outcome has not been improved despite the knowledge on inflammatory processes; a reason for these lack of results may lay on the lack of data on the precise dynamics of inflammatory and anti-inflammatory cascades and their consequences. We intend to achieve accurate monitoring of the inflammatory process on a small group of non-immunocompromised patients. Our goal is to obtain quality data, repeated over time, by limiting the technical variability.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Evaluation of Immunosuppression in Septic Shock: Biomarkers and Pharmacological Restoration (IMMUNOSEPSIS)

NCT02803346

Immunology of Septic Shock

UNKNOWN

Septic Shock-induced Immunosuppression

NCT04067674

Septic Shock

RECRUITING

Evaluation of the Performance of the IDBIORIV Method in Pathogen Identification and Antibiotic Susceptibility Testing in Patients With Sepsis

NCT06219135

Sepsis

RECRUITING

Immune Homeostasis in Sepsis and Septic Shock

NCT04448951

Sepsis Immunologic Paralysis Immunologic Suppression +1 more

RECRUITING

Clinical Intuition for PRedicting Evolution in Sepsis in the Emergency Department - CIPRES-ED Study

NCT04803942

Sepsis

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The aim is to obtain precise data on the dynamics of cytokines, oxydative stress and hormonal response on immunocompetent adults during septic shock.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Immunocompetent Patient on Septic Shock

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient over 18 years admitted in ICU.
* Clinical evidence of infection, suspected or proved, during the 48hrs following the hospital entry.
* Systemic inflammatory response syndrome.
* Shock defined as arterial hypotension (\<90mmHg)not responding to adequated filling.

Exclusion Criteria

* Minors
* Patient under guardianship or trusteeship
* Pregnant or lactating women
* Not affiliated to the social security
* Deprived of liberty by court decision
* Patients hospitalised without their approval
* Shock related to another cause than infection
* Long term corticothérapy
* On-going chemiothérapy, AIDS
* Bedridden patient

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No