Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
3000 participants
OBSERVATIONAL
2014-08-31
2028-03-31
Brief Summary
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Detailed Description
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Registered data can be used for quality control and clinical research to reduce sepsis-related mortality.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* suspected or proven infection
* any organ dysfunction as follows:
1. cardiovascular (hypotension, systolic blood pressure \<90 mmHg, mean arterial pressure \<70mmHg)
2. tissue hypoperfusion (lactate above upper limits laboratory normal)
3. acute lung injury (PaO2/inspired oxygen fraction \< 250 in the absence of pneumonia, PaO2/inspired oxygen fraction \< 200 in the presence of pneumonia)
4. acute kidney injury (Urine output \< 0.5mL/kg/hr for at least 2 hrs Serum creatinine \> 2.0 mg/dL)
5. acute liver injury (Total bilirubin \> 2mg/dL)
6. acute coagulopathy (Platelet count \< 100,000/μL or prothrombin time, international normalized ratio \> 1.5)
Exclusion Criteria
* patients with cardiac arrest at presentation
* patients with advanced directives not to deliver aggressive organ supportive management
18 Years
ALL
No
Sponsors
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Seoul National University Bundang Hospital
OTHER
Seoul National University Boramae Hospital
OTHER
Hallym University Kangnam Sacred Heart Hospital
OTHER
Gangnam Severance Hospital
OTHER
Kyungpook National University Hospital
OTHER
Kyunghee University Medical Center
OTHER
Korea University Guro Hospital
OTHER
Korea University Anam Hospital
OTHER
The Catholic University of Korea
OTHER
Samsung Medical Center
OTHER
Asan Medical Center
OTHER
Severance Hospital
OTHER
Ulsan University Hospital
OTHER
Inje University Ilsan Paik Hospital
OTHER
Chonnam National University Hospital
OTHER
Chonbuk National University Hospital
OTHER
Jeju National University Hospital
OTHER
Chosun University Hospital
OTHER
Hallym University Medical Center
OTHER
Hanyang University Seoul Hospital
OTHER
Bucheon St. Mary's Hospital
OTHER
Seoul National University Hospital
OTHER
Responsible Party
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Gil Joon Suh
Professor
Principal Investigators
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Gil Joon Suh, MD, PhD
Role: STUDY_DIRECTOR
Seoul National University Hospital
Locations
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Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea
Seoul National University Hospital
Seoul, , South Korea
Seoul Metropolitan Government-Seoul National University Boramae Medical Center
Seoul, , South Korea
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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1408-003-599
Identifier Type: -
Identifier Source: org_study_id