Prognostic Interest of Leucocyte Immunophenotyping During the Acute Phase of Sepsis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-11-30

Study Completion Date

2015-06-30

Brief Summary

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Septic shock is still a major cause of death in ICU. Sepsis diagnosis is linked with many clinical, hemodynamic and biological criteria which have a low sensitivity and specificity if they are considered separately. The extensive experimental data which have been published contrast with the hematological data collected by the physician at patient's bedside especially regarding neutrophils and platelets levels. When there is no obvious clinical sign, a biological tool reflecting the patient's immune status could be useful to understand the physiopathology of Sepsis and to predict the progression of the disease in the patient. On the long-term it could also help to define management strategies.

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Detailed Description

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Conditions

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Sepsis With Acute Organ Dysfunction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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SEPSIS Blood test

Patient with two criteria of systemic inflammatory response syndrome and a progressive infection which is clinically or microbiologically documented.

Blood test

Intervention Type BIOLOGICAL

Residue of blood further to NFS.

Interventions

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Blood test

Residue of blood further to NFS.

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* patient older than 18 years old
* Patient with two criteria of systemic inflammatory response syndrome and a progressive infection which is clinically or microbiologically documented