Safety and Feasibility of Reversible Induction Strategy

NCT ID: NCT04434963

Last Updated: 2021-09-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-01

Study Completion Date

2021-12-01

Brief Summary

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This study would explore the safety and feasibility of a reversible induction strategy for uncertain difficult airway. This reversible induction strategy would include high flow nasal canular oxygenation support, short-term effect anesthetic including Propofol and Remifentanil for sedation and analgesia and Sugammadex would be used for reverse the muscle relaxant.

Detailed Description

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Conditions

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Patients With Uncertain Difficult Airway Colon Cancer Gastric Cancer Prostatic Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* \>18 years old,\<65 years old
* Signed informed consent
* Undergoing selective operation ( time of operation is over two hours)
* ASA classification I-II
* Mallampati classification 3-4
* suspicious difficult airway, but the anesthetists decide to try to rapid induction

Exclusion Criteria

* Patients with several dysfunctions of liver, kidney or heart)
* Patients with a full stomach or have other risk factors of reflux aspiration
* Any medicine was taken before surgery, which might enhance or mitigate the effects of muscle relaxant
* Infection of the mouth or nose
* Allergy history of any medicine which would be used in this study
* Pregnant and lactating women
* Patients with neuromuscular disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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RenJi Hospital

OTHER

Sponsor Role lead

Responsible Party

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diansan su

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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diansan su

Role: STUDY_DIRECTOR

Renji Hospital, Shanghai Jiaotong University, Shanghai, China

Locations

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Ren Ji Hospital Affliated to School of Medicine, Shanghai Jiao Tong University

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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diansan su

Role: CONTACT

+862168383702

Xiaoying Chi, M.S.

Role: CONTACT

+86 18201706040

Facility Contacts

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diansan su

Role: primary

+862168383702

Other Identifiers

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RenjiH6502

Identifier Type: -

Identifier Source: org_study_id

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