Effect of Processed Blueberry on Blood Glucose and Antioxidant Status in Human Adults

NCT ID: NCT04396262

Last Updated: 2023-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-01

Study Completion Date

2022-08-31

Brief Summary

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Canada's Food Guide (2007) recommended 7-10 servings of fruits and vegetables per day for a normal adult population. Although fruit juice (125 ml) is considered as one serving of fruits, the consumption of some fruit juices may be limited due to their high amount of sugar. The consumption of sugary drinks can lead to a rapid rise in postprandial glycaemia. Wild blueberries, due to their high level of anthocyanins, may provide multiple health benefits including improved blood glucose control, however, the consumption of fresh berries is limited by their short seasonal availability. Hydro-Thermodynamic (HTD) processing of blueberries allows the processing of whole berries including their skin and seeds into a beverage with the amount of anthocyanins comparable with fresh berries. The objective of the study is to investigate the effect of HTD-processed blueberries on postprandial glycaemia and antioxidant activity.

Detailed Description

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Conditions

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Blood Glucose

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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HTD-blueberry beverage with white bread

The beverage prepared using hydro-thermodynamic processing of whole wild blueberries.

Group Type EXPERIMENTAL

Food-1

Intervention Type OTHER

HTD-blueberry beverage with white bread.

Sweetened water (control) with white bread

The water control of the same volume and with the same amount of available carbohydrate as HTD-blueberry beverage.

Group Type EXPERIMENTAL

Food-2

Intervention Type OTHER

Sweetened water with white bread as a control.

Interventions

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Food-1

HTD-blueberry beverage with white bread.

Intervention Type OTHER

Food-2

Sweetened water with white bread as a control.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Healthy adults
* Body mass index (BMI) within normal range (18.5-24.9 kg/m2 for adults)

Exclusion Criteria

* Chronic metabolic diseases or inflammatory conditions
* Smokers
* A medication that influences glucose control or gastrointestinal function
* Known allergies
* Intellectual disabilities
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Mount Saint Vincent University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bohdan Luhovyy, PhD

Role: PRINCIPAL_INVESTIGATOR

Mount Saint Vincent University

Locations

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Mount Saint Vincent University

Halifax, Nova Scotia, Canada

Site Status

Countries

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Canada

Other Identifiers

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2015-102

Identifier Type: OTHER

Identifier Source: secondary_id

2019-204

Identifier Type: -

Identifier Source: org_study_id

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