1,3,7-Trimethylxanthine as a Treatment of COVID-19: Results of a Controlled Study

NCT ID: NCT04395742

Last Updated: 2020-05-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

93 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-31

Study Completion Date

2020-12-31

Brief Summary

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This is observational study to assess the prognosis of patients hospitalized with COVID-19 confirmed by RT-PCR and exposed to trimethylxanthine (TMX).

Trimethylxanthine is the active molecule present in coffee. Due to the lack of etiologic treatments and considering interest about old treatments as an avenue for research, we conducted a comparative study aiming to evaluate the effect of 1,3,7-trimethylxanthine on COVID-19 infected patients. This is actually a study about methodology.

The objective of this study is therefore not to demonstrate the effect of the substance on the disease but the importance of a rigorous methodology in scientific research. This project is called "Method and Teaching of Scientific Studies".

Detailed Description

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Conditions

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Coronavirus Disease 2019

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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Coffee:1,3,7-trimethylxanthine

Data collection

Intervention Type OTHER

Only data collection

Tea and hot chocolate with milk

Data collection

Intervention Type OTHER

Only data collection

Interventions

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Data collection

Only data collection

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age \> 18,
* No Trimethylxanthine contraindications (defined as allergy, previous reported secondary effects),
* Infectious Disease Unit admission.

Exclusion Criteria

* Secondary effects about Trimethylxanthine,
* Refuse to participate
Minimum Eligible Age

18 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Poitiers University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Alexandre BLEIBTREU

Role: CONTACT

142163303 ext. 0033

Paul ROBLOT

Role: CONTACT

References

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Belaroussi Y, Roblot P, Peiffer-Smadja N, Delaye T, Mathoulin-Pelissier S, Lemeux J, Le Moal G, Caumes E, Roblot F, Bleibtreu A. Why Methodology Is Important: Coffee as a Candidate Treatment for COVID-19? J Clin Med. 2020 Nov 17;9(11):3691. doi: 10.3390/jcm9113691.

Reference Type DERIVED
PMID: 33213035 (View on PubMed)

Other Identifiers

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TMX COVID

Identifier Type: -

Identifier Source: org_study_id

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