Determination of the Levels of Lipocalin-2 and Semaphorin3A
NCT ID: NCT04390997
Last Updated: 2021-02-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
60 participants
INTERVENTIONAL
2019-11-15
2021-01-15
Brief Summary
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Detailed Description
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Possible significant differences may illuminate the future work with Lipocalin-2 and Semaphorin 3A. Also, these glycoproteins may help to develop different diagnostic methods or treatment strategies for future periodontal treatments.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
SINGLE
Study Groups
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Periodontally Healthy
20 participants with bleeding on probing less than 10%, probing depths less than 4mm, and no clinical attachment loss which was measured by six sites per tooth
No interventions assigned to this group
Gingivitis
20 participants with bleeding on probing greater than 10%, probing depths less than 4mm, and no clinical attachment loss which was measured by six sites per tooth
No interventions assigned to this group
Periodontitis
20 participants with bleeding on probing greater than or equal to 30%, probing depths greater than or equal to 5mm at least non-adjacent two teeth in each quadrant of the dentition, and clinical attachment loss greater than or equal to 4mm which was measured by six sites per tooth, and radiographic bone loss on the coronal third of root or severe (vertical/ horizontal) bone loss.
Non-surgical Periodontal Treatment
Non-surgical periodontal treatment includes scaling and root planning by using curettes and ultrasonic devices only in the periodontitis group.
Interventions
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Non-surgical Periodontal Treatment
Non-surgical periodontal treatment includes scaling and root planning by using curettes and ultrasonic devices only in the periodontitis group.
Eligibility Criteria
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Inclusion Criteria
* Having at least 20 teeth in the dentition, excluding third molars
* Not using alcohol nor smoking
* Not using medications
* Not taking any antibiotics, anti-inflammatory, nor systemic corticosteroid drugs in the last six months
* Not being in the lactation period nor pregnancy
Exclusion Criteria
* Using alcohol or smoking
* Using medications
* Taking any antibiotics, anti-inflammatory, or systemic corticosteroid drugs in the last six months
* Being in the lactation period or pregnancy
* Being treated with periodontal treatment in the last six months
18 Years
70 Years
ALL
Yes
Sponsors
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Izmir Katip Celebi University
OTHER
Responsible Party
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Merve Ceylan
Research Assistant
Locations
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Izmir Katip Celebi University, Faculty of Dentistry
Izmir, Cigli, Turkey (Türkiye)
Countries
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Other Identifiers
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2019-TDU-DİSF-0009
Identifier Type: -
Identifier Source: org_study_id
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