Description of Ophthalmologic Injuries in Intensive Care During the SARS-CoV2 Epidemic - COVID19

NCT ID: NCT04385810

Last Updated: 2026-01-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-04-27

Study Completion Date

2020-07-29

Brief Summary

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The management of patients with SARS-CoV2 in respiratory distress can expose to corneal or retinal lesions induced by the stay in intensive care.

Examination by ophthalmologists would make it possible to detect the most of the ophthalmologic problems known in intensive care and to provide an early, preventive or curative therapeutic response when possible, in order to avoid irreversible visual loss.

The object of the research is to assess the presence and the importance of surface ophthalmologic lesions, the presence and the importance of retinal or optic nerve lesions, in order to improve the monitoring and primary prevention of this population

Detailed Description

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Conditions

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Covid19 Sars-CoV2

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Ophthalmologic exam

Group Type EXPERIMENTAL

Ophthalmologic exam

Intervention Type PROCEDURE

Direct exam and Slit lamp exam Shirmer test Retinophotography At inclusion, day 7, day 14 and discharge from hospital

Interventions

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Ophthalmologic exam

Direct exam and Slit lamp exam Shirmer test Retinophotography At inclusion, day 7, day 14 and discharge from hospital

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* patient SARS-CoV2 positive (RT-PCR or chest scanner)
* hospitalized in intensive care

Exclusion Criteria

* traumatic lesion of the face or any other condition preventing any ophthalmological evaluation
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fondation Ophtalmologique Adolphe de Rothschild

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean Michel DEVYS, MD

Role: PRINCIPAL_INVESTIGATOR

Fondation Adolphe de Rothschild

Locations

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Fondation Adolphe de Rothschild

Paris, , France

Site Status

Countries

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France

References

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Stephan S, Cohen F, Salviat F, Thevenin S, Devys JM, Cochereau I, Gabison E. Evaluation of the impact of intensive care support for COVID-19 on the ocular surface in a prospective cohort of 40 eyes. Ocul Surf. 2021 Oct;22:13-14. doi: 10.1016/j.jtos.2021.06.008. Epub 2021 Jun 23. No abstract available.

Reference Type RESULT
PMID: 34174393 (View on PubMed)

Other Identifiers

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JDS_2020_13

Identifier Type: -

Identifier Source: org_study_id

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