Evaluation of Retinal Microvascular Change That May Develop in After Open Globe Injury
NCT ID: NCT05771467
Last Updated: 2025-01-16
Study Results
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View full resultsBasic Information
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COMPLETED
100 participants
OBSERVATIONAL
2024-03-02
2024-09-02
Brief Summary
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Detailed Description
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As one of the most severe forms of ocular trauma, open-globe injury (OGI) causes significant vision loss. Timely and meticulous repair of these injuries can improve patient outcomes.
OGI by rupture often occurs at the weakest point of the eye wall, which may or may not be at the actual injury site. The rupture site is most commonly found in the sclera concentric to the limbus, just posterior to the insertion of the extraocular muscles.
After trauma, changes may occur in the non-trauma eye. Retinal and choroidal circulation may change as a result of adaptation mechanisms. In this study, we evaluated the vascular densities of the control group and post-traumatic non-trauma eye.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Trauma Group
Non-trauma eye after open globe injury determine retinal microvascular changes
Comprehensive Ophthalmologic Examination
Measurements of best-corrected visual acuity, refractive error, intraocular pressure, axial length, slit lamp examination of the anterior segment, dilated fundus examination, and anterior segment parameters, optical coherence tomography angiography (OCTA)
Control Group
Investigation of retinal microvascular circulation in age- and sex-matched healthy volunteers
Comprehensive Ophthalmologic Examination
Measurements of best-corrected visual acuity, refractive error, intraocular pressure, axial length, slit lamp examination of the anterior segment, dilated fundus examination, and anterior segment parameters, optical coherence tomography angiography (OCTA)
Interventions
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Comprehensive Ophthalmologic Examination
Measurements of best-corrected visual acuity, refractive error, intraocular pressure, axial length, slit lamp examination of the anterior segment, dilated fundus examination, and anterior segment parameters, optical coherence tomography angiography (OCTA)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Unilateral eye injury
Exclusion Criteria
* Usage of systemic drugs or topical ocular drops
* Bilateral eye injury
* Having systemic disease, having ocular pathology that may decrease visual acuity
18 Years
ALL
Yes
Sponsors
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Akdeniz University
OTHER
Responsible Party
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Aslı Çetinkaya Yaprak
Associate Professor
Principal Investigators
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Yusuf Samet Atlıhan, MD, 1
Role: PRINCIPAL_INVESTIGATOR
Akdeniz University Hospital
Locations
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Aslı Çentinkaya Yaprak
Antalya, , Turkey (Türkiye)
Yusuf Samet Atlıhan
Antalya, , Turkey (Türkiye)
Countries
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Provided Documents
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Document Type: Study Protocol and Statistical Analysis Plan
Document Type: Informed Consent Form
Other Identifiers
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AKDENIZ-GOZ-001
Identifier Type: -
Identifier Source: org_study_id
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