NIV and CPAP Failure Predictors in COVID-19 Associated Respiratory Failure
NCT ID: NCT04342104
Last Updated: 2021-08-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2020-04-01
2021-11-15
Brief Summary
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Propose adaptations to HACOR score based on the "state of art" of COVID-19
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Detailed Description
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Propose adaptations to HACOR score based on the "state of art" of COVID-19
\- this adaptations may include radiologic aggravation and monitoring of CRF, ferritin, LDH, d-dimers, NT-proBNP, troponin I, GOT, GPT, blood count
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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NIV
Patients on Bilevel NIV
Monitoring for aggravation
Monitor patients on CPAP or NIV and analyzing possible variables that may predict failure, namely:
* lymphopenia
* thrombocytopenia
* CRP
* ferritin
* LDH
* troponin I
* NT-ProBNP
* Liver enzymes
* D-dimers
* radiologic aggravation " 1 day and 1 week after starting NIV or CPAP
Evaluate HACOR score effectivity in this patients
Apply the HACOR score after starting NIV and CPAP and later verify if it was effective in predicting NIV/CPAP failure
CPAP
Patients on CPAP
Monitoring for aggravation
Monitor patients on CPAP or NIV and analyzing possible variables that may predict failure, namely:
* lymphopenia
* thrombocytopenia
* CRP
* ferritin
* LDH
* troponin I
* NT-ProBNP
* Liver enzymes
* D-dimers
* radiologic aggravation " 1 day and 1 week after starting NIV or CPAP
Evaluate HACOR score effectivity in this patients
Apply the HACOR score after starting NIV and CPAP and later verify if it was effective in predicting NIV/CPAP failure
Interventions
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Monitoring for aggravation
Monitor patients on CPAP or NIV and analyzing possible variables that may predict failure, namely:
* lymphopenia
* thrombocytopenia
* CRP
* ferritin
* LDH
* troponin I
* NT-ProBNP
* Liver enzymes
* D-dimers
* radiologic aggravation " 1 day and 1 week after starting NIV or CPAP
Evaluate HACOR score effectivity in this patients
Apply the HACOR score after starting NIV and CPAP and later verify if it was effective in predicting NIV/CPAP failure
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* Patients with any formal contraindication to noninvasive respiratory support
18 Years
ALL
No
Sponsors
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Hospital General Universitario Morales Meseguer
OTHER
Responsible Party
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Miguel Filipe Martins de Matos Navarro Guia
Dr.
Principal Investigators
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Miguel Guia
Role: PRINCIPAL_INVESTIGATOR
Hospital General Universitario Morales Meseguer
Antonio Esquinas
Role: STUDY_DIRECTOR
Hospital General Universitario Morales Meseguer
Locations
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Hospital General Universitario Morales Meseguer
Murcia, , Spain
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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08-04-2020
Identifier Type: -
Identifier Source: org_study_id
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