Noninvasive Respiratory Support in COVID-19 (CATCOVID-AIR)
NCT ID: NCT04668196
Last Updated: 2021-04-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
367 participants
OBSERVATIONAL
2020-05-22
2021-01-25
Brief Summary
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Detailed Description
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During the hospitalization, patients were treated according to the standard procedures of the participating centers. This study is observational and no randomization have been performed.
Patients were followed up to either 28-days or hospital discharge if still hospitalized at day 28 from NIRS initiation.
Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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High-flow nasal cannula treatment
High-flow nasal cannula treatment
Standard operating procedures represented by hihg-flow nasal cannula oxygen therapy
Continuous positive airway pressure (CPAP) treatment
Continuous positive airway pressure (CPAP) treatment
Standard operating procedures represented by continuous positive airway pressure (CPAP) therapy
Noninvasive ventilation treatment
Noninvasive ventilation treatment
Standard operating procedures represented by noninvasive ventilation treatment
Interventions
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High-flow nasal cannula treatment
Standard operating procedures represented by hihg-flow nasal cannula oxygen therapy
Continuous positive airway pressure (CPAP) treatment
Standard operating procedures represented by continuous positive airway pressure (CPAP) therapy
Noninvasive ventilation treatment
Standard operating procedures represented by noninvasive ventilation treatment
Eligibility Criteria
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Inclusion Criteria
* Acute respiratory failure.
* Treated by noninvasive respiratory support (nasal high-flow oxygen, CPAP or noninvasive ventilation), initiated outside the intensive care unit.
* Age \> 18 years
Exclusion Criteria
* Hypercapnic acute respiratory failure
* Early intolerance to treatment
* Nosocomial infection
* Pregnant woman
18 Years
ALL
No
Sponsors
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Barcelona Institute for Global Health
OTHER
Hospital Universitari Vall d'Hebron Research Institute
OTHER
Responsible Party
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Principal Investigators
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Júlia Sampol, MD
Role: STUDY_CHAIR
Hospital Universitari Vall d'Hebron Research Institute
Sergi Marti, MD PhD
Role: PRINCIPAL_INVESTIGATOR
Hospital Universitari Vall d'Hebron Research Institute
Locations
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Hospital Germans Trias i Pujol
Badalona, Barcelona, Spain
Hospital General de Granollers
Granollers, Barcelona, Spain
Hospital de Bellvitge
L'Hospitalet de Llobregat, Barcelona, Spain
Fundació Althaia
Manresa, Barcelona, Spain
Corporació Sanitària Parc Taulí
Sabadell, Barcelona, Spain
Hospital Universitari Mútua Terrassa
Terrassa, Bardelona, Spain
Hospital del Mar, Parc de Salut Mar
Barcelona, , Spain
Hospital de la Santa Creu i Sant Pau
Barcelona, , Spain
Hospital Vall d'Hebron
Barcelona, , Spain
Hospital Dr.Josep Trueta
Girona, , Spain
Countries
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References
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Marti S, Carsin AE, Sampol J, Pallero M, Aldas I, Marin T, Lujan M, Lalmolda C, Sabater G, Bonnin-Vilaplana M, Penacoba P, Martinez-Llorens J, Tarrega J, Bernadich O, Cordoba-Izquierdo A, Lozano L, Mendez S, Velez-Segovia E, Prina E, Eizaguirre S, Balana-Corbero A, Ferrer J, Garcia-Aymerich J. Higher mortality and intubation rate in COVID-19 patients treated with noninvasive ventilation compared with high-flow oxygen or CPAP. Sci Rep. 2022 Apr 20;12(1):6527. doi: 10.1038/s41598-022-10475-7.
Other Identifiers
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PR(AG)265/2020
Identifier Type: -
Identifier Source: org_study_id
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