Clinical Trial Assessing Two Protocols to Withdraw Non-invasive Ventilation in Hypercapnic Respiratory Failure
NCT ID: NCT00775710
Last Updated: 2011-06-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
128 participants
INTERVENTIONAL
2006-03-31
2010-08-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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1
Non-invasive ventilation is maintained during three nights after recovery of an episode of hypercapnic respiratory failure.
Nocturnal non-invasive ventilation
Prolongation of non-invasive ventilation during 3 nights.
2
Discontinuation of NIV after the recovery of hypercapnic respiratory failure, without prolong it during night.
No interventions assigned to this group
Interventions
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Nocturnal non-invasive ventilation
Prolongation of non-invasive ventilation during 3 nights.
Eligibility Criteria
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Inclusion Criteria
* Use of NIV to treat respiratory failure.
* Persistence of hypercapnia after discontinuation of NIV
Exclusion Criteria
* Facial or cranial trauma or surgery,
* Recent gastric or esophageal surgery,
* Active upper gastrointestinal bleeding,
* Excessive amount of respiratory secretions,
* Tracheostomy
* Lack of cooperation
ALL
No
Sponsors
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Hospital Clinic of Barcelona
OTHER
Responsible Party
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Respiratoy Intensive Care Unit
Principal Investigators
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Jacobo Sellares, MD
Role: PRINCIPAL_INVESTIGATOR
Hospital Clinic
Locations
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Hospital del Mar
Barcelona, Barcelona, Spain
Hospital de Sant Pau
Barcelona, Barcelona, Spain
Hospital Clinic
Barcelona, Barcelona, Spain
Countries
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References
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Sellares J, Ferrer M, Anton A, Loureiro H, Bencosme C, Alonso R, Martinez-Olondris P, Sayas J, Penacoba P, Torres A. Discontinuing noninvasive ventilation in severe chronic obstructive pulmonary disease exacerbations: a randomised controlled trial. Eur Respir J. 2017 Jul 5;50(1):1601448. doi: 10.1183/13993003.01448-2016. Print 2017 Jul.
Other Identifiers
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NIV-JS1
Identifier Type: -
Identifier Source: org_study_id
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