Psychiatry of Transition in a World in Transition

NCT ID: NCT04333797

Last Updated: 2026-01-07

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 252 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-06-10
• Study Completion Date: 2023-12-31

Brief Summary

This clinical study evaluates risk and protective factor to develop psychopathology in transitional age youth. 300 patients will be recruited at the age of 17 years old and assessed at baseline and 2 years later.

Detailed Description

Emerging adults are a particularly at-risk population in mental health. Transitional age youth have specific needs, not currently covered between child and adolescent mental health services (CAMHS) and adult mental health services (AMHS), mainly because of existing barriers. Movements from one to the other must be planned to achieve optimal patient care.

Our project aims to identify clinical dimensional characteristics contributing to the development of psychopathology during the transition period. Continuities, discontinuities and resilience factors will be explored. The final purpose is to develop a non-stigmatizing approach to reduce rejection from youths in psychopathological suffering and increase social inclusion.

The transversal and trans-diagnostic approach consists of a dimensional evaluation: 300 youth at the age of 17 will be included in a cohort of in-patients, out-patients and control group. Participants will be assessed at baseline and 2 years later. The primary outcome is based on Health of the Nation Outcome Scale for Children and Adolescents, measuring mental health care need, and WHO Quality of Life assessment.

The secondary outcomes include the assessment of dimensions representing risk or protective factors to develop psychopathology and evolution of mental health status during transition age. Baseline evaluation consists in internalizing/externalizing symptoms, impulsivity/compulsivity, emotion regulation, cognitive functioning, social and family functioning, developmental, medical and trauma history. At follow-up, mental health pathways and transition results will be described.

Conditions

Transitional Care; Mental Disorder in Adolescence; Mental Health

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Transitional age youth

Assessed group.

Group Type: OTHER

Risk and Protective Factors Assessment

Intervention Type: OTHER

First assessment at baseline (T0) - 17 y.o. Follow-up 2 years later (T1) - 19 y.o.

Interventions

Risk and Protective Factors Assessment

First assessment at baseline (T0) - 17 y.o. Follow-up 2 years later (T1) - 19 y.o.

Intervention Type: OTHER

Other Intervention Names

Transitional care from CAMHS to AMHS

Eligibility Criteria

Inclusion Criteria

• French-speaking and French-understanding
• Subjects who accepted to participated to the study (signature of informed consent/assent document from subjects and parents or legal holder of parental authority)
• Specific criteria for patients: inpatients and out-patients
• Specific criteria for control group: youth from general population or placed in residential centres

Exclusion Criteria

• Impossibility to answer to the assessment tools
• Medium intellectual disability (homogenous IQ < 75)
• Presence of a grave somatic disease (cancer, cardiac failure, renal failure, central nervous system disorder), that is progressive or that affects the vital prognosis in the short term
• Active participation to another study

• Minimum Eligible Age: 17 Years
• Maximum Eligible Age: 17 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Erasme University Hospital

OTHER

Sponsor Role: collaborator

Brugmann University Hospital

OTHER

Sponsor Role: collaborator

Service santé mentale à l'ULB

UNKNOWN

Sponsor Role: collaborator

Université Libre de Bruxelles

OTHER

Sponsor Role: collaborator

King Baudouin Foundation

OTHER

Sponsor Role: collaborator

Queen Fabiola Children's University Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Véronique Delvenne, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Queen Fabiola Children's University Hospital

Locations

Brugmann University Hospital

Brussels, , Belgium

Hôpital Universitaire Des Enfants Reine Fabiola

Brussels, , Belgium

Service santé mentale à l'ULB

Brussels, , Belgium

Erasme University Hospital

Brussels, , Belgium

Countries

Belgium

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Reis J, Marchini S, De Leeuw A, Slama H, Leys C, Delhaye M, Kornreich C, Nicolis H, Delvenne V. Study Protocol: Transition_psy a Multicenter Prospective Longitudinal Cohort Study Assessing Risk and Protective Factors to Develop Psychopathology in Transitional Age Youth in Belgium. Front Psychiatry. 2021 Jun 21;12:645679. doi: 10.3389/fpsyt.2021.645679. eCollection 2021.

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Other Identifiers

P2020/PSY/Transition_psy

Identifier Type: -

Identifier Source: org_study_id