Symptoms and Mechanisms of Child Psychiatric Disorders

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

218 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-09-01

Study Completion Date

2023-12-31

Brief Summary

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In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present in children referred to outpatient psychiatric clinics. A specific focus will be given to children suffering from severe irritability.

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Detailed Description

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In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present in children referred to outpatient psychiatric service. A specific focus will be given to children suffering from severe irritability making problems at home, in school, and/or with peers.

Disruptive Mood Dysregulation Disorder (DMDD) is characterized by chronic and severe irritability and anger in children. DMDD understood as severe or clinical irritability can be regarded as laying above a certain threshold on a irritability continuum. Due to DMDD being a relatively new and debated diagnosis there is an urgent need to gain better understanding of the underlying mechanisms of severe irritability in children.

This study will explore emotion and behavior symptoms, neuropsychological functions (including social perception), perceived parental stress and attachment styles, and cortisol levels of children and their mothers, in children referred to outpatient psychiatric service including children with severe irritability. Parents of children 6 to 12 years will be informed and asked to participate.

The work on severe irritability will be divided into six main areas:

1. Severe irritability in a Norwegian clinical population: prevalence, comorbidity and associated difficulties
2. Social and emotional understanding in severe irritability in children
3. Executive function in severe irritability in children
4. Stress response in severe irritability in children
5. Parental stress and attachment style in parents of severe irritability in children
6. DMDD: An affective or conduct disorder? Comparing anxiety and depressive symptoms

Conditions

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Disruptive Mood Dysregulation Disorder Attention Deficit Hyperactivity Disorder Oppositional Defiant Disorder Severe Irritability Child Psychiatric Disorders

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Children referred to outpatient clinic

Diagnostic interview (Schedule for Affective Disorders and Schizophrenia (K-SADS) cf. Diagnostic and Statistical Manual of Mental Disorders (DSM-5)) with parents. Diagnostic groups/cohorts (e.g., DMDD, ADHD, Oppositional Defiant Disorder) will be based on the diagnoses given cf. K-SADS.

No interventions assigned to this group

Typical developing children and their parent(s)

Norm values on hair cortisol data will be obtained from typical developing children and their parent(s) by the same procedure as described under Outcome measure(s), 21. Stress Response by Cortisol levels.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Referred to outpatient psychiatric service
* Intelligence quotient (IQ) within normal range
* Child and parents: Good enough understanding of Norwegian language to give valid answers in interview and tests.
* Clarified care situation

Exclusion Criteria

* IQ below normal range
* Child and parents: Not good enough understanding of Norwegian language to give valid answers in interview and tests
* Unclarified care situation

Minimum Eligible Age

6 Years

Maximum Eligible Age

12 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No