Development of a Transdiagnostic Intervention for Adolescents at Risk for Serious Mental Illness

NCT ID: NCT05962879

Last Updated: 2025-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-22

Study Completion Date

2027-07-31

Brief Summary

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This research study aims to develop a brief group-based treatment called Resilience Training for Teens, then to test how well it protects high school students with mild symptoms of depression, anxiety, or having unusual feelings from developing mental illnesses.

Detailed Description

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Conditions

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Anxiety Disorders Psychotic Disorders Depressive Disorder Psychosocial Functioning

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Resilience Training for Teens

A brief 6-session group-based behavioral intervention for teens at risk of a mental illness.

Group Type EXPERIMENTAL

Resilience Training for Teens

Intervention Type BEHAVIORAL

A brief 6-session group-based behavioral intervention for high school aged teenagers at risk of a mental illness.

Waitlist

A one year waitlist period where participants will not participate in Resilience Training for Teens. Following that one year waitlist period, they can participate in Resilience Training for Teens.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Resilience Training for Teens

A brief 6-session group-based behavioral intervention for high school aged teenagers at risk of a mental illness.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Currently enrolled in 9th through 12th grade and between the ages of 14 and 19
* Endorsed at least one psychotic experience
* Provided contact information
* Have a parent or legal guardian who is able and willing to provide written informed consent (if under the age of 18)
* Have a parent or legal guardian who is able and willing to participate in a parent session
* Competent and willing to provide written informed assent (if under the age of 18) or consent (if age 18 or older)
* Able to communicate in English

Exclusion Criteria

* Currently prescribed psychotropic medication (not including medications for attention deficit/hyperactivity disorder), regardless of adherence
* Currently obtaining psychotherapeutic intervention
Minimum Eligible Age

14 Years

Maximum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

Massachusetts General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Nicole DeTore, PhD

Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Massachusetts General Hospital

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Nicole R DeTore, PhD

Role: CONTACT

617-726-2065

Facility Contacts

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Nicole R DeTore, PhD

Role: primary

Other Identifiers

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K23MH131793

Identifier Type: NIH

Identifier Source: secondary_id

View Link

2023P000985

Identifier Type: -

Identifier Source: org_study_id

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