Reducing Health Risk Behavior and Improving Health in Adolescents With Depression

NCT ID: NCT00461539

Last Updated: 2022-11-03

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: PHASE1/PHASE2
• Total Enrollment: 217 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2007-10-31
• Study Completion Date: 2012-01-31

Brief Summary

This study will determine the effectiveness of a health education intervention in reducing health risk behavior and improving health in adolescents with depression.

Detailed Description

Depression is a common disorder among adolescents. If left untreated, it can cause significant disability, illness, and even death. Teens with depression often engage in risky health behaviors, such as smoking, drug and alcohol use, unprotected sex, and unhealthy eating and exercise patterns. By reducing these health risk behaviors, depressed adolescents may be able to avoid negative health consequences and improve their physical and mental health. This study will determine the effectiveness of a health education intervention in reducing risky health behaviors in adolescents with depression.

Participants in this study will be invited to enroll during a visit to a participating primary care clinic. Participants will be randomly assigned to either partake in a health education intervention or receive standard care. Both groups will continue to receive treatment through their primary care clinic. Those participants receiving standard care will be referred to special programs as needed to reduce their involvement in risky health behaviors. Participants assigned to the health education intervention will attend 10 weekly education sessions that will be led by trained health educators. Parents or guardians may be asked to attend sessions depending on their interest in the intervention and the age of the youth participant. Topics covered will include teenage smoking, alcohol and drug abuse, risky sexual behaviors, and obesity. Cognitive-behavioral strategies, role playing, and media clips will be used to stimulate discussion and involvement in the intervention. The intervention will be tailored to target the specific risky behaviors in which each participant engages. Motivational interviewing will also be used to build positive attitudes to support behavior change. All participants will attend follow-up visits to assess behavior change at Months 6 and 12 following study entry.

Conditions

Depression; Adolescent Health

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

2

Participants will receive treatment as usual

Group Type: ACTIVE_COMPARATOR

Treatment as usual

Intervention Type: OTHER

Those participants receiving standard care will be referred to special programs as needed to reduce their involvement in risky health behaviors.

1

Participants will receive the behavioral health intervention

Group Type: EXPERIMENTAL

Behavioral health intervention

Intervention Type: BEHAVIORAL

Participants assigned to the health education intervention will attend 10 weekly education sessions that will be led by trained health educators. Parents or guardians may be asked to attend sessions depending on their interest in the intervention and the age of the youth participant. Topics covered will include teenage smoking, alcohol and drug abuse, risky sexual behaviors, and obesity. Cognitive-behavioral strategies, role playing, and media clips will be used to stimulate discussion and involvement in the intervention.

Interventions

Treatment as usual

Those participants receiving standard care will be referred to special programs as needed to reduce their involvement in risky health behaviors.

Intervention Type: OTHER

Behavioral health intervention

Participants assigned to the health education intervention will attend 10 weekly education sessions that will be led by trained health educators. Parents or guardians may be asked to attend sessions depending on their interest in the intervention and the age of the youth participant. Topics covered will include teenage smoking, alcohol and drug abuse, risky sexual behaviors, and obesity. Cognitive-behavioral strategies, role playing, and media clips will be used to stimulate discussion and involvement in the intervention.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• CIDI diagnosis of major depression or probable depression based on youth self report
• Availability of a family member to provide informed consent

Exclusion Criteria

• Lacks contact information (e.g., address, telephone number)
• Any functioning deficits or other characteristics that might interfere with study participation
• Currently in a living situation that might interfere with study participation (e.g., lives over 1 hour away from the study site)
• Lacks family available to participate in the intervention
• Mental retardation
• Does not speak English or Spanish

• Minimum Eligible Age: 13 Years
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute of Mental Health (NIMH)

NIH

Sponsor Role: collaborator

Kaiser Permanente Research Foundation

UNKNOWN

Sponsor Role: collaborator

University of California, Los Angeles

OTHER

Sponsor Role: lead

Responsible Party

Joan Asarnow

Professor of Psychiatry & Biobehavioral Sciences

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Joan Asarnow, PhD

Role: PRINCIPAL_INVESTIGATOR

University of California, Los Angeles, Semel Institute of Neuroscience and Human Behavior

Locations

University of California, Los Angeles, Semel Institute for Neuroscience and Human Behavior

Los Angeles, California, United States

Kaiser Permanente Los Angeles Medical Center

Los Angeles, California, United States

Countries

United States

References

Bai S, Zeledon LR, D'Amico EJ, Shoptaw S, Avina C, LaBorde AP, Anderson M, Fitzpatrick OM, Asarnow JR. Reducing Health Risk Behaviors and Improving Depression in Adolescents: A Randomized Controlled Trial in Primary Care Clinics. J Pediatr Psychol. 2018 Oct 1;43(9):1004-1016. doi: 10.1093/jpepsy/jsy048.

Reference Type: BACKGROUND

PMID: 30016473 (View on PubMed)

Asarnow JR, Zeledon LR, D'Amico E, LaBorde A, Anderson M, Avina C, Arslanian T, Do MC, Harwood J, Shoptaw S. Depression and Health Risk Behaviors: Towards Optimizing Primary Care Service Strategies for Addressing Risk. Prim Health Care. 2014 Mar 1;4(1):152. doi: 10.4172/2167-1079.1000152.

Reference Type: BACKGROUND

PMID: 25309826 (View on PubMed)

Other Identifiers

R01MH078596

Identifier Type: NIH

Identifier Source: secondary_id

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DAHBR 96-BHB

Identifier Type: -

Identifier Source: secondary_id

R01MH078596

Identifier Type: NIH

Identifier Source: org_study_id

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