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Rumination-focused CBT Training for the Prevention of Depression and Anxiety

NCT ID: NCT01223677

Last Updated: 2014-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

251 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-10-31

Study Completion Date

2014-09-30

Brief Summary

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Depression and anxiety disorders are highly prevalent and associated with reduced quality of life for patients and enormous economic costs for society. Although effective treatments are available, a substantial number of patients fail to respond, and the time between disorder onset and treatment is typically long. The development of prevention programs therefore appears promising. The current project aims to prevent depression and anxiety by targeting excessive levels of worry and rumination, two important risk factors for emotional disorders. Participants will be selected on the basis of a high score on two validated questionnaires on worry and rumination. They will be randomly assigned to a rumination-focused cognitive-behavioral training delivered in a group format, a rumination-focused cognitive-behavioral training delivered via internet, or a no-training control condition. It is expected that both versions of the rumination-focused training will reduce symptoms of depression and anxiety, will reduce the incidence of major depressive episodes and generalized anxiety disorder, and will reduce symptom levels of other emotional disorders.

Detailed Description

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see above

Conditions

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Depression Anxiety Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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rumination focused CBT

RFCBT-group. This group training is based on research showing that dysfunctional forms of rumination are characterized by an abstract evaluative style of processing, whereas functional forms of of processing are more concrete and process-focused. The training uses psycho-education, functional analysis, group discussion, experiential exercises and behavioral experiments to facilitate the shift from dysfunctional ruminative thinking to a more helpful concrete thinking style.

Group Type ACTIVE_COMPARATOR

Rumination Focused CBT

Intervention Type BEHAVIORAL

see arms

rumination focused CBT (online)

The online training is based on research showing that dysfunctional forms of rumination are characterized by an abstract evaluative style of processing, whereas functional forms of of processing are more concrete and process-focused. The training uses psycho-education, functional analysis, experiential exercises and behavioral experiments to facilitate the shift from dysfunctional ruminative thinking to a more helpful concrete thinking style.

Group Type ACTIVE_COMPARATOR

Rumination Focused CBT

Intervention Type BEHAVIORAL

see arms

No training control group

No training control group. Participants within this condition received no treatment, but only filled out the outcome measures at each measurement period.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Rumination Focused CBT

see arms

Intervention Type BEHAVIORAL

Other Intervention Names

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RFCBT

Eligibility Criteria

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Inclusion Criteria

* A score above the 75% and 66.7% percentile on two validated self-report measures of rumination and worry, the Ruminative Response Scale of the Response Style Questionnaire (RSQ; Nolen-Hoeksema \& Morrow, 1991), and the Penn State Worry Questionnaire (PSWQ; Meyer et al. 1990).

Exclusion Criteria

* A score indicating fulfillment of DSM-IV criteria for depression or generalized anxiety disorder according to the Patient Health Questionnaire-9 (PHQ-9; Kroenke, Spitzer, \& Williams, 2001) or the Generalized Anxiety Disorder Questionnaire-IV (GADQ-IV; Newman et al., 2002)
Minimum Eligible Age

15 Years

Maximum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

Sponsor Role collaborator

VU University of Amsterdam

OTHER

Sponsor Role lead

Responsible Party

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Thomas Ehring

PhD.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Thomas Ehring, PhD

Role: PRINCIPAL_INVESTIGATOR

Westfalische Wilhelms Universitat Munster

Locations

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University of Amsterdam

Amsterdam, North Holland, Netherlands

Site Status

Countries

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Netherlands

References

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Watkins ER, Moberly NJ. Concreteness training reduces dysphoria: a pilot proof-of-principle study. Behav Res Ther. 2009 Jan;47(1):48-53. doi: 10.1016/j.brat.2008.10.014. Epub 2008 Oct 21.

Reference Type BACKGROUND
PMID: 19036353 (View on PubMed)

Other Identifiers

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50-50105-96-635

Identifier Type: -

Identifier Source: org_study_id