Non-Invasive Positive Pressure Ventilation Management of High Altitude Pulmonary Edema
NCT ID: NCT04288219
Last Updated: 2020-09-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
16 participants
INTERVENTIONAL
2020-03-01
2021-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Standard of Care Treatment
Continuous supplemental oxygen and nifedipine 30mg will be administered to patients.
Nifedipine
Nifedipine 30mg, Pharmacotherapy
supplemental oxygen
supplemental oxygen
Non-Invasive Positive Pressure Ventilation Management
CPAP at 10mmHg with supplemental oxygen, as well as nifedipine 30mg will be administered to patients.
Non-Invasive Positive Pressure Ventilation
Continuous positive airway pressure delivered by face mask at 10cmH2O
Nifedipine
Nifedipine 30mg, Pharmacotherapy
Interventions
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Non-Invasive Positive Pressure Ventilation
Continuous positive airway pressure delivered by face mask at 10cmH2O
Nifedipine
Nifedipine 30mg, Pharmacotherapy
supplemental oxygen
supplemental oxygen
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Travel through Pheriche, Nepal
* Diagnosis of HAPE by symptoms, vital signs, and lung ultrasound
Exclusion Criteria
* Concomitant pneumonia or aspiration, cardiomyopathy, congestive heart failure
* Kidney disease
* Neurologic disorder
* Cognitive disorder
* Temporary altered mental status
* Use of phosphodiesterase inhibitors or nifedipine prior to diagnosis of HAPE
* Age under 18 or over 80
* Pregnancy
18 Years
80 Years
ALL
Yes
Sponsors
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Himalayan Rescue Association
UNKNOWN
Massachusetts General Hospital
OTHER
Responsible Party
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N. Stuart Harris MD MFA
Chief, Division of Wilderness Medicine, Principal Investigator, Clinical Innstructor
Locations
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Himalayan Rescue Association
Kathmandu, , Nepal
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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2019P003234
Identifier Type: -
Identifier Source: org_study_id
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