Clinical Study of Titrating PEEP of Different Methods on Right Heart Function

NCT ID: NCT03845556

Last Updated: 2019-02-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-04

Study Completion Date

2019-03-30

Brief Summary

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To observe the influence of different methods titrating PEEP on right heart function and pulmonary artery pressure in ARDS patients .

Detailed Description

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30 patients who diagnosed as ARDS were included in this study.Then set PEEP with respectively ARDS net 、EIT and Esophageal Pressure in Breathing Machine . Recorded diameter of right and left ventricular TAM TAPSE pulmonary artery pressure.Objective to evaluate the correlation between the level of PEEP in three methods and the right heart function and pulmonary artery pressure in ARDS patients .

Conditions

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ARDS, Human

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients admitted to ICU diagnosed of modecate to severe ARDS (Berlin criteria)
* Patients age between 18 years old and 80 years

Exclusion Criteria

* Patients with chronic respiratory diseases such as COPD.
* Ventilated because of oesophageal surgery in the previous 12months.
* Patients who cannot obtain clear ultrasound images due to thoracic surgery ,massive pleural effusion.
* Oesophageal bleeding in previous 30 days history of oesophageal varices.
* Facial trauma and surgery.
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Zhongda Hospital

OTHER

Sponsor Role collaborator

Southeast University, China

OTHER

Sponsor Role lead

Responsible Party

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Chun Pan

Clinical Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Chun Pan, Dr

Role: PRINCIPAL_INVESTIGATOR

southeast university

Locations

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Zhongda Hospital

Nanjing, Jiangsu, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Dutong Yue, Dr

Role: CONTACT

15051887681

GuoFeng Mei, Dr

Role: CONTACT

13813841261

Facility Contacts

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Feng Mei Guo, Dr

Role: primary

13813841261

Other Identifiers

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ARDS

Identifier Type: -

Identifier Source: org_study_id

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