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Diaphragm Ultrasound to Predict Weaning Outcomes in Mechanically Ventilated Patients

NCT ID: NCT03480828

Last Updated: 2018-03-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

36 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-04-01

Study Completion Date

2017-12-31

Brief Summary

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This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation.

Detailed Description

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This trial enrolled all the adult patients who were mechanically ventilated for more than 48 hours and met all creteria for extubation. Patients who needed reintubation for upper aiway obstruction, neurological or hemodynamic alteration were excluded. The diaphragm ultrasound was performed during spontaneous breathing test or pressure support ventilation trial measuring the dipahragmatic excursion (DE) and the diaphragm thickening fraction (DTF) whithin 24 hours before extubation. The investigators compared the median values of DE and DTF in the group of successfully extubated patients and the group of patients who needed reintubation.

Our study compared the utility of DTF and DE to predict extubation success.

Conditions

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Accuracy of DE and DTF in Prediction of Extubation Success

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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comparaison between DE and DTF in prediction of extubation success

diaphragm ultrasound and measurement of DE and DTF in patients meeting all extubation criteria during spontaneous breathing trial

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* patients who were mechanically ventilated for more than 48h and meeting all criteria for extubation
* patients without history of neuromuscular disease, or severe chronic respiratory failure

Exclusion Criteria

* patients who needed reintubation for upper airway obstruction or neurological or hemodynamic instability
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mongi Slim Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mhamed Sami Mebazaa

Professor head of the anesthesia and intensive care department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mhamed Sami Mebazaa, Professor

Role: PRINCIPAL_INVESTIGATOR

Mongi Slim Hospital

Locations

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Mongi Slim Hospital

La Marsa, Tunis Governorate, Tunisia

Site Status

Countries

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Tunisia

Other Identifiers

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rea1

Identifier Type: -

Identifier Source: org_study_id