ECMO for COVID-19 vs Influenza A H1N1 Associated ARDS

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

308 participants

Study Classification

OBSERVATIONAL

Study Start Date

2009-08-22

Study Completion Date

2021-02-28

Brief Summary

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Objective: Veno-venous ECMO has been used as a rescue therapy for patients with severe ARDS associated to influenza A H1N1 and COVID19 viral pneumonia. Little is known about outcome of these patients who required extracorporeal support.

Research question: To compare outcome of patients who required VV ECMO for Covid19 and H1N1 associated ARDS

Detailed Description

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Conditions

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ARDS COVID-19 H1N1 Influenza

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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COVID-19

No interventions assigned to this group

H1N1

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* COVID-19 or influenza A H1N1 (suspected or confirmed) diagnosis
* Severe ARDS (according to Berlin Definition)
* VV ECMO
* Invasive mechanical ventilation through endotracheal tube or tracheostomy

Exclusion Criteria

• Age\<18 years

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Vito Fanelli MD, PhD

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Turin - Azienda Ospedaliera Città della Salute e della Scienza di Torino

Turin, , Italy

Site Status

Countries

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Italy

References

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Fanelli V, Giani M, Grasselli G, Mojoli F, Martucci G, Grazioli L, Alessandri F, Mongodi S, Sales G, Montrucchio G, Pizzi C, Richiardi L, Lorini L, Arcadipane A, Pesenti A, Foti G, Patroniti N, Brazzi L, Ranieri V. Extracorporeal membrane oxygenation for COVID-19 and influenza H1N1 associated acute respiratory distress syndrome: a multicenter retrospective cohort study. Crit Care. 2022 Feb 5;26(1):34. doi: 10.1186/s13054-022-03906-4.

Reference Type DERIVED

PMID: 35123562 (View on PubMed)

Other Identifiers

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v1_12_2020

Identifier Type: -

Identifier Source: org_study_id