Remineralization of Caries Affected Dentin

NCT ID: NCT04262076

Last Updated: 2020-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-06-01

Study Completion Date

2020-01-01

Brief Summary

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Remineralization of carious affected dentin

Detailed Description

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Remineralization of Carious affected dentin by using Pulpine alone and combination of Pulpine with Polyamidoamine Dendrimer.

Conditions

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Deep Caries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

split mouth design
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Combination of pulpine with Polyamidoamine Dendrimer

Removal of Caries infected dentin from the walls and floor of the cavity and then apply polyamidoamine Denrimer for 30 secs ,then washed out of the cavity followed by placement of Pulpine over affected Dentin.

Group Type EXPERIMENTAL

Pulpine with Polyamidoamine Dendrimer

Intervention Type OTHER

Removal of infected dentin in class I Cavities followed by application of Polyamidoamine Denrimer on caries affected Dentin that is washed out of the cavity after 30 secs then finally place Pulpine .

Pulpine

Removal of Caries infected dentin from the walls and the floor of the cavity followed by application of Pulpine over affected Dentin.

Group Type ACTIVE_COMPARATOR

Pulpine with Polyamidoamine Dendrimer

Intervention Type OTHER

Removal of infected dentin in class I Cavities followed by application of Polyamidoamine Denrimer on caries affected Dentin that is washed out of the cavity after 30 secs then finally place Pulpine .

Interventions

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Pulpine with Polyamidoamine Dendrimer

Removal of infected dentin in class I Cavities followed by application of Polyamidoamine Denrimer on caries affected Dentin that is washed out of the cavity after 30 secs then finally place Pulpine .

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Presence of at least one class one carious posterior teeth in both left and right side.
* Absence of spontaneous pain, Mobility and tenderness on percussion.

Exclusion Criteria

* Patients with poor oral Hygiene.
* Evidence of Rampant Caries.
* Teeth with periodontal involvement.
* Poor general health condition.
Minimum Eligible Age

18 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Al-Azhar University

OTHER

Sponsor Role lead

Responsible Party

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Mona Rizk Abo El Wafa Ahmed

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al-Azhar University, Faculty of Dentistry for Girls

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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REC17-01123

Identifier Type: -

Identifier Source: org_study_id

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