Management of Occlusal Caries Using Silver Modified Atraumatic Restorative Treatment Versus Atraumatic Restorative Treatment

NCT ID: NCT04354636

Last Updated: 2024-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2/PHASE3

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-01

Study Completion Date

2023-10-11

Brief Summary

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Silver modified atraumatic restorative treatment (intervention) or atraumatic restorative treatment (Control) will be used to manage occlusal caries in preschool children then the molars will be evaluated at the interval of 3,6 and 12 months clinically and 6 and 12 months radiographically

Detailed Description

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Aim of the study:

To evaluate the clinical and radiographic outcomes after the use of silver modified atraumatic restorative treatment versus atraumatic restorative treatment in the management of occlusal caries in primary molars in preschool children.

PICO:

Population:

Preschool children (4-6 years) with occlusal caries in second primary molars.

Intervention:

Silver modified atraumatic restorative treatment

Comparator/Control:

Atraumatic restorative treatment.

Outcomes:

Pain (provoked or spontaneous) OHRQoL(oral health related to quality of life) Parental esthetic perception Failure of restoration Caries density in radiograph

Time:

3, 6 and 12 months

Study design:

A randomized clinical trial

Conditions

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Occlusal Caries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Silver modified atraumatic restorative treatment

Using silver diamine fluoride incorporated with atraumatic restorative treatment

Group Type EXPERIMENTAL

Silver modified atraumatic restorative treatment

Intervention Type DRUG

Silver diamine fluoride that will be applied during atraumatic restorative treatment

Atraumatic restorative treatment

Using atraumatic restorative treatment without the application of silver diamine fluoride

Group Type ACTIVE_COMPARATOR

Atraumatic restorative treatment

Intervention Type OTHER

Using atraumatic restorative treatment without applying silver diamine fluoride

Interventions

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Silver modified atraumatic restorative treatment

Silver diamine fluoride that will be applied during atraumatic restorative treatment

Intervention Type DRUG

Atraumatic restorative treatment

Using atraumatic restorative treatment without applying silver diamine fluoride

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* • Patient and parent cooperation and compliance.

* Children aged 4 - 6 years
* Second primary molars with occlusal caries.
* No clinical signs and symptoms of pulp involvement
* No radiographic abnormalities

Exclusion Criteria

* • Uncooperative children or parents

* Children with systemic diseases
* Children with previous allergies to any of the used materials
Minimum Eligible Age

4 Years

Maximum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Mennatallah Sameh Ahmed Farouk Abdelhamid

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sherif B El Tawil, Professor

Role: STUDY_DIRECTOR

Pediatric Dentistry & Dental Public Health Faculty of Dentistry , Cairo university

Dalia M Moheb, Associate professor

Role: STUDY_DIRECTOR

Pediatric Dentistry & Dental Public Health Faculty of Dentistry , Cairo university

Locations

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Faculty's pediatric dentiatry clinic

Cairo, Gizq, Egypt

Site Status

Countries

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Egypt

References

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Vollu AL, Rodrigues GF, Rougemount Teixeira RV, Cruz LR, Dos Santos Massa G, de Lima Moreira JP, Luiz RR, Barja-Fidalgo F, Fonseca-Goncalves A. Efficacy of 30% silver diamine fluoride compared to atraumatic restorative treatment on dentine caries arrestment in primary molars of preschool children: A 12-months parallel randomized controlled clinical trial. J Dent. 2019 Sep;88:103165. doi: 10.1016/j.jdent.2019.07.003. Epub 2019 Jul 4.

Reference Type BACKGROUND
PMID: 31279925 (View on PubMed)

Saber AM, El-Housseiny AA, Alamoudi NM. Atraumatic Restorative Treatment and Interim Therapeutic Restoration: A Review of the Literature. Dent J (Basel). 2019 Mar 7;7(1):28. doi: 10.3390/dj7010028.

Reference Type BACKGROUND
PMID: 30866534 (View on PubMed)

Oliveira BH, Rajendra A, Veitz-Keenan A, Niederman R. The Effect of Silver Diamine Fluoride in Preventing Caries in the Primary Dentition: A Systematic Review and Meta-Analysis. Caries Res. 2019;53(1):24-32. doi: 10.1159/000488686. Epub 2018 Jun 6.

Reference Type BACKGROUND
PMID: 29874642 (View on PubMed)

van Gemert-Schriks MC, van Amerongen WE, ten Cate JM, Aartman IH. Three-year survival of single- and two-surface ART restorations in a high-caries child population. Clin Oral Investig. 2007 Dec;11(4):337-43. doi: 10.1007/s00784-007-0138-8. Epub 2007 Aug 21.

Reference Type BACKGROUND
PMID: 17710452 (View on PubMed)

Other Identifiers

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SMART_ART

Identifier Type: -

Identifier Source: org_study_id