Impact of Suppressing Surgical Stress Reaction on Postoperative Inflammation.
NCT ID: NCT04195009
Last Updated: 2019-12-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2019-12-01
2021-12-31
Brief Summary
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Detailed Description
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total dose of each drug and duration of anesthesia are recorded. Antinociceptive devices measures how long the patient is during anesthesia having a nociceptive level nociception level index (NOL) or Analgesia Nociception Index (ANI) above normal without showing the data to the attending anesthesiologist.
Relationship is calculated between on one side the hemodynamic stability, postoperative sedation, pain, postoperative CRP and on the other side the time NOL is above 20 or ANI is below 50.
Conditions
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Study Design
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OTHER
PROSPECTIVE
Interventions
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major surgery under opioid free anesthesia without regional anesthesia
measuring nociception in every patient but blinded for attending anesthesiologist
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* major liver, renal cardiac or pulmonary disease reducing normal function
18 Years
ALL
No
Sponsors
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AZ Sint-Jan AV
OTHER
Responsible Party
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Jan Mulier
Principal investigator
Principal Investigators
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Jan Paul Mulier, MD PhD
Role: PRINCIPAL_INVESTIGATOR
AZ Sint-Jan AV
Locations
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Azsintjan
Bruges, , Belgium
Countries
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Central Contacts
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Other Identifiers
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OS impact SSR on SIRS d OFA
Identifier Type: -
Identifier Source: org_study_id