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Interactions of Brain Regions in Visuomotor Adaptation

NCT ID: NCT04190940

Last Updated: 2019-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

39 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-04-18

Study Completion Date

2021-04-17

Brief Summary

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The purpose of this study is to better understand the roles the cerebellum, basal ganglia, and thalamus play in motor learning. Patients undergoing High Intensity Focused Ultrasound (HIFU) treatment will be receiving an ablation procedure to their thalamus as a part of their medical procedure. Participation in this study will include completing a behavioral task before and after the procedure to see how motor learning task performance differs with and without the thalamus. Similarly, patients undergoing Deep Brain Stimulation (DBS) treatment will have an electrode implanted in their thalamus as a part of their medical procedures. Participation in this study will include completing the motor learning task performance "on" and "off" thalamic electrical stimulation.

Detailed Description

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Conditions

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High Intensity Focused Ultrasound Deep Brain Stimulation

Keywords

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Ultrasound Thalamus Cerebellum Basal Ganglia Deep Brain Stimulation High Intensity Focused Ultrasound

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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High Intensity Focused Ultrasound

Patients receiving high intensity focused ultrasound as a treatment will be asked to complete the behavioral task pre and post their treatment.

Group Type EXPERIMENTAL

Behavioral Assessment

Intervention Type BEHAVIORAL

Patients will be asked to complete the behavioral assessment before and after their HIFU treatment or "on" and "off" their DBS treatment.

Deep Brain Stimulation

Patients receiving deep brain stimulation as a treatment will be asked to complete the behavioral task while their DBS electrode is "on" and "off".

Group Type EXPERIMENTAL

Behavioral Assessment

Intervention Type BEHAVIORAL

Patients will be asked to complete the behavioral assessment before and after their HIFU treatment or "on" and "off" their DBS treatment.

Interventions

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Behavioral Assessment

Patients will be asked to complete the behavioral assessment before and after their HIFU treatment or "on" and "off" their DBS treatment.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Be a patient receiving either high intensity focused ultrasound treatment or deep brain stimulation treatment for Tremor
* Able to provide informed consent and complete study procedures
* Must speak English
* Age 18-85

* Unable to provide consent or complete study procedures
* Women who self-report pregnancy
* Patients who are currently incarcerated
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Virginia

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University of Virginia

Charlottesville, Virginia, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Sarah Adams

Role: CONTACT

Phone: 4342434319

Email: [email protected]

Facility Contacts

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Sarah Adams

Role: primary

Other Identifiers

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21483

Identifier Type: -

Identifier Source: org_study_id