Study of Different Endoscopic Preparations Used in Pediatric Colonoscopy

NCT ID: NCT04153084

Last Updated: 2019-11-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

126 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-10-01

Study Completion Date

2019-12-31

Brief Summary

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The aim of this study is to evaluate the quality, acceptance, tolerability and adverse effects of colonoscopy preparations with the different available preparation guidelines.

Detailed Description

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Conditions

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Digestive Illness

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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High volume electrolytes Polyethylene Glycol (PEG 4000) cohort

Pediatric patients who have prepared for a colonoscopy during the years 2018-2019 using high volume electrolytes PEG (Bohm solution®) endoscopic preparation, as part of a diagnostic procedure not related to this study.

Polyethylene Glycol 4000 with electrolytes

Intervention Type DRUG

The high volume electrolytes PEG will be administered at a 4 mg/kg dose the day before the procedure in 4-8 hours.

Low volume electrolytes PEG (PEG 3350) cohort

Pediatric patients who have prepared for a colonoscopy during the years 2018-2019 using low volume electrolytes PEG (Movicol®) endoscopic preparation, as part of a diagnostic procedure not related to this study.

PEG-3350 with electrolytes

Intervention Type DRUG

The low volume electrolytes PEG will be administered at a 4 mg/kg dose the day before the procedure in 4-8 hours.

Sodium picosulfate cohort

Pediatric patients who have prepared for a colonoscopy during the years 2018-2019 using sodium picosulfate (Picoprep®) endoscopic preparation, as part of a diagnostic procedure not related to this study.

Sodium picosulfate

Intervention Type DRUG

The Sodium picosulfate will be administered the day before the procedure at different doses depending on the patient´s age:

* From 1 to 2 years old: ¼ sachet reconstituted in ¼ glass of water/juice in the afternoon (15:00 h) and ¼ sachet reconstituted in ¼ glass of water/juice 6 hours later (21:00 h)
* From 2 to 4 years old: ½ sachet in ½ glass of water/juice in the afternoon and ½ sachet in ½ glass of water/juice at night.
* From 4 to 9 years old: 1 sachet in 1 glass of water/juice in the afternoon and ½ sachet in ½ glass of water/juice at night.
* Of 9 years old and older: 1 sachet in the afternoon and 1 sachet at night.

Interventions

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Polyethylene Glycol 4000 with electrolytes

The high volume electrolytes PEG will be administered at a 4 mg/kg dose the day before the procedure in 4-8 hours.

Intervention Type DRUG

PEG-3350 with electrolytes

The low volume electrolytes PEG will be administered at a 4 mg/kg dose the day before the procedure in 4-8 hours.

Intervention Type DRUG

Sodium picosulfate

The Sodium picosulfate will be administered the day before the procedure at different doses depending on the patient´s age:

* From 1 to 2 years old: ¼ sachet reconstituted in ¼ glass of water/juice in the afternoon (15:00 h) and ¼ sachet reconstituted in ¼ glass of water/juice 6 hours later (21:00 h)
* From 2 to 4 years old: ½ sachet in ½ glass of water/juice in the afternoon and ½ sachet in ½ glass of water/juice at night.
* From 4 to 9 years old: 1 sachet in 1 glass of water/juice in the afternoon and ½ sachet in ½ glass of water/juice at night.
* Of 9 years old and older: 1 sachet in the afternoon and 1 sachet at night.

Intervention Type DRUG

Other Intervention Names

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Bohm solution® Movicol® Picoprep®

Eligibility Criteria

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Inclusion Criteria

* From 1 to 16 years old.
* Patients that signed the informed consent form.

Exclusion Criteria

* Urgent colonoscopy
* History of intestinal resection
* Nephropathy, heart disease or metabolic syndrome.
Minimum Eligible Age

1 Year

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fundación Pública Andaluza para la gestión de la Investigación en Sevilla

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alejandro Rodríguez Martínez

Role: PRINCIPAL_INVESTIGATOR

Hospital Universitario Virgen Rocío

Locations

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Hospital Universitario Puerta del Mar

Cadiz, Cádiz, Spain

Site Status NOT_YET_RECRUITING

Complejo Hospitalario Torrecárdenas

Almería, , Spain

Site Status NOT_YET_RECRUITING

Hospital Materno-Infantil de Badajoz

Badajoz, , Spain

Site Status NOT_YET_RECRUITING

Hospital Universitario Reina Sofía

Córdoba, , Spain

Site Status NOT_YET_RECRUITING

Hospital Universitario Virgen de las Nieves

Granada, , Spain

Site Status NOT_YET_RECRUITING

Hospital Universitario Virgen Macarena

Seville, , Spain

Site Status RECRUITING

Hospital Universitario Virgen del Rocío

Seville, , Spain

Site Status RECRUITING

Instituto Hispalense de Pediatría

Seville, , Spain

Site Status NOT_YET_RECRUITING

Countries

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Spain

Central Contacts

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Alejandro Rodríguez Martínez

Role: CONTACT

955012000

Facility Contacts

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Cristina Pérez Aragón

Role: primary

Rafael Galera Martínez

Role: primary

Ana María Márquez Armenteros

Role: primary

Rafael González de Caldas Marchal

Role: primary

María Medina Gil

Role: primary

Carmen Cuadrado Caballero

Role: primary

Alejandro Rodríguez Martínez

Role: primary

Joaquín Reyes Andrade

Role: primary

Other Identifiers

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FIS-POL-2017-01

Identifier Type: -

Identifier Source: org_study_id

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