One-Day Versus Three-Day Bowel Preparation for Colonoscopy in Children

NCT ID: NCT02174497

Last Updated: 2014-06-25

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 32 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2008-02-29
• Study Completion Date: 2010-06-30

Brief Summary

This was a blinded study conducted on the efficacy and safety of a one-day versus a three-day bowel preparation in a pediatric population. Limited data is available in this regard, and this study supports the use of a one-day bowel preparation, as this is both safe and effective.

Detailed Description

Colonoscopy in children and young adults is performed by gastroenterologists for a variety of indications, including but not limited to evaluation of rectal bleeding, chronic diarrhea, family history of polyposis syndromes and surveillance for colon cancer in patients with inflammatory bowel disease. A successful bowel preparation that enables clear visualization of the intestinal mucosa is essential to diagnose and treat the underlying pathology. Currently, gastroenterologists use a variety of colon cleansing preparations, but Polyethylene Glycol (PEG) 3350 given for three to four days appears to be standard. Though it is well tolerated, safe and effective the duration of preparation may cause disruption to the routine and missed school days. To date, there is limited data that shows efficacy of a shorter duration of bowel preparation with PEG. This study aims to compare the efficacy and safety of a one-day preparation with that of a three-day preparation with PEG 3350 as preparation for colonoscopy in children and young adults.

Conditions

Bowel Preparation; Pediatric Colonoscopy

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Control

Three day Bowel Preparation

No interventions assigned to this group

Study Arm

One day Bowel Preparation

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Pediatric Patients referred for an outpatient colonoscopy

Exclusion Criteria

• None

• Minimum Eligible Age: 2 Years
• Maximum Eligible Age: 21 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

St. John Health System, Michigan

OTHER

Sponsor Role: lead

Responsible Party

Hernando Lyons, MD

Clinical Assistant Professor of Pediatrics

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

St. John Hospital and Medical Center

Detroit, Michigan, United States

Countries

United States

References

Sorser SA, Konanki V, Hursh A, Hagglund K, Lyons H. 1-day bowel preparation with polyethylene glycol 3350 is as effective and safe as a 3-day preparation for colonoscopy in children. BMC Res Notes. 2014 Sep 15;7:648. doi: 10.1186/1756-0500-7-648.

Reference Type: DERIVED

PMID: 25223547 (View on PubMed)

Other Identifiers

OMB No 0925-0586

Identifier Type: -

Identifier Source: org_study_id