Interactive Stepping Exercise on Memory

NCT ID: NCT04103463

Last Updated: 2019-09-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-10-01

Study Completion Date

2021-07-31

Brief Summary

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This is a randomized controlled trail. A total of 28 individuals with aMCI will be randomly assigned to either the ISE group or control group. The ISE intervention conducts three times a week for 16 weeks. Outcomes are measured at baseline and after intervention. The primary outcomes are the Chinese version verbal learning test (CVVLT), selective reminding test (SRT), and logic memory test (Wechsler Memory Scale). The secondary outcomes are Montreal Cognitive Assessment (MoCA) for cognitive function, and trail making test Part A \& B (TMT-A \& B), Stroop test, and 25-item Executive Interview (C-EXIT 25) for executive function.

Detailed Description

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Conditions

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Amnestic Mild Cognitive Impairment Interactive Stepping Exercise Memory Cognitive Function Executive Function

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Interactive stepping exercise group

Group Type EXPERIMENTAL

Interactive stepping exercise

Intervention Type OTHER

An exercise intervention based on the principle of square stepping exercise

Home exercise group

Group Type ACTIVE_COMPARATOR

Home exercise

Intervention Type OTHER

Home exercise

Interventions

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Interactive stepping exercise

An exercise intervention based on the principle of square stepping exercise

Intervention Type OTHER

Home exercise

Home exercise

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age≥50 years
* Complained of memory impairment
* Chinese Version Verbal Learning Test 10-minute delays ≤ 6 words
* MMSE score≥24 and CDR score=0.5
* Activities of daily living are intact
* DSM-IV criteria for the diagnosis of dementia is not met

Exclusion Criteria

* Any significant neurologic disease other than suspected incipient Alzheimer's disease
* Psychotic features, contraindication of exercise... which could lead to difficulty complying with the protocol
Minimum Eligible Age

50 Years

Maximum Eligible Age

100 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Yang Ming Chiao Tung University

OTHER

Sponsor Role lead

Responsible Party

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Yea-Ru Yang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Yea-Ru Yang

Role: CONTACT

+886228267279

Other Identifiers

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YM108072F

Identifier Type: -

Identifier Source: org_study_id

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