Combined Motor and Cognitive Training for Older Adults With Motoric Cognitive Risk Syndrome (CMC-training)

NCT ID: NCT06542601

Last Updated: 2024-08-07

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 204 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-07-04
• Study Completion Date: 2025-06-30

Brief Summary

To investigate the effects of a combined motor-cognitive intervention on the improvement of motor as well as cognitive function in community residents.

Detailed Description

Cognitive training uses systematically designed tasks that are difficulty-adaptive for cognitive domains such as attention, memory, and logical reasoning to improve individual cognitive functioning. Internet-based Adaptive Multi-Cognitive Domain Cognitive Training is conducted 3 times per week for 30 minutes each time, and includes tasks such as delayed memory, paired memory, and inverse numerical breadth.

The exercise intervention was based on the M-Mobile multicomponent exercise program, in which older adults were instructed to complete exercise training at home at least three days per week. In all intervention groups, balance, sitting test and walking speed were assessed according to the Simple Physical Performance Battery (SPPB), and according to their scores, they were given exercise training, including flexibility, balance, aerobic training and resistance training.

Conditions

Disability Physical; Disabilities Mental; Age Problem

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Total

All subjects

Motor cognitive intervention

Intervention Type: DEVICE

Older adults were given cognitive training and motor training for 12 weeks using a tablet computer

Interventions

Motor cognitive intervention

Older adults were given cognitive training and motor training for 12 weeks using a tablet computer

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Age 60-80 years; ≥ 9 years of education; Cognitive impairment: MMSE score 22-26; Slow gait:total walking time >4 seconds and ≤8 seconds in a 4-meter walk test; Agreed to participate in the study and signed an informed consent form.

Exclusion Criteria

• Dementia/suspected dementia; Suffering from diseases that affect cognitive function, such as cerebrovascular disease, Parkinson's syndrome, etc.; Taking medications related to cognitive improvement and psychiatric disorders, etc.; Recent heart attack, severe cerebrovascular disease, psychiatric disorders, etc.; other inability to persist in completing exercise cognitive interventions, such as suffering from severe musculoskeletal disorders; Participating in another clinical trial at the same time； Participation in an exercise and/or cognitive intervention in the past 6 months; Inability to complete content in studies such as neuropsychological scale assessments.

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Xuanwu Hospital, Beijing

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Yi Tang, MD., PhD.

Role: PRINCIPAL_INVESTIGATOR

Xuanwu Hospital, Beijing

Locations

Xuanwu Hospital, Capital Medical University

Beijing, , China

Site Status: RECRUITING

Countries

China

Central Contacts

Yi Tang, MD., PhD.

Role: CONTACT

tangyi@xwhosp.org

00861083199456

Facility Contacts

Yi Tang, M.D., Ph.D.

Role: primary

00861083199456

Other Identifiers

2022-234

Identifier Type: -

Identifier Source: org_study_id