Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
24 participants
INTERVENTIONAL
2019-08-22
2023-01-01
Brief Summary
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Detailed Description
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To systematically map out the components of the overfed state, the investigators will execute a 2-week randomized controlled overfeeding trial in lean and overweight individuals. The trial is preceded by a 1-week lead-in period and followed by a 2-wk controlled ad libitum study period. The comparison between lean and overweight subjects, men and women, enables the determination of whether a differential response in overfeeding-induced signals is present in relation to BMI and sex.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
SINGLE
Study Groups
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Control group
Subjects in this group will have a daily energy intake equivalent of 100 % of their calculated normal daily energy intake.
Isocaloric diet
Two weeks of isocaloric weight maintenance
Overfed group
Subjects in this group will have a daily energy intake equivalent of 150 % of their calculated normal daily energy intake.
Overfeeding diet
Two weeks of overfeeding
Interventions
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Overfeeding diet
Two weeks of overfeeding
Isocaloric diet
Two weeks of isocaloric weight maintenance
Eligibility Criteria
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Inclusion Criteria
* 20-40 years of age
* BMI (Body mass index) between 22-30 kg/m2
Exclusion Criteria
* smoking
* more than 3 hours of planned physical activity per week
20 Years
40 Years
ALL
Yes
Sponsors
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University of Copenhagen
OTHER
Responsible Party
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Christoffer Clemmensen
Associate Professor
Principal Investigators
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Christoffer Clemmensen, Assoc. Prof.
Role: PRINCIPAL_INVESTIGATOR
Assoc. prof. NNF Center for Basic Metabolic Research
Locations
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University of Copenhagen
Copenhagen, Norrebro, Denmark
Countries
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Other Identifiers
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ExpO
Identifier Type: -
Identifier Source: org_study_id
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