Effects of Intravenous Anesthesia on Postoperative Cognitive Function in Patients Accepted Painless Gastroenteroscopy

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-08-01

Study Completion Date

2020-06-01

Brief Summary

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The investigators want to study the effect of intravenous anesthesia on postoperative cognitive function in patients accepted gastroenteroscopy ,no additional medication or operation is involved

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Detailed Description

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The investigators want to study the effect of intravenous anesthesia on postoperative cognitive function in patients accepted gastroenteroscopy ,no additional medication or operation is involved.The investigators assess cognitive function through a series of tests for 4 times( within 3 days before the endoscopy ,2 hours after the endoscopy finished,1 week after the endoscopy,3 months after the endoscopy),including WCST、DSST、DST、HADS、MoCA,through self - contrast,the investigators will conclude whether intravenous anesthesia has bad impact on cognitive function or not .

Conditions

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Postoperative Cognitive Function

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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A: anesthesia group

Patients accepting endoscopy check under anesthesia will be included in this group as group A,will doing a series of tests

a series of tests

Intervention Type BEHAVIORAL

all patients in every group will do a series of tests,including DSST、DST、MoCA、WCST、HADS

B:Non-anesthesia group

patients undergoing endoscopy check without anesthesia will be included in this group as controls voluntarily,namely group B,will doing a series of tests

a series of tests

Intervention Type BEHAVIORAL

all patients in every group will do a series of tests,including DSST、DST、MoCA、WCST、HADS

Interventions

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a series of tests

all patients in every group will do a series of tests,including DSST、DST、MoCA、WCST、HADS

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* voluntary to participate in
* Vital signs are stable
* no drug or alcohol abuse
* no mental illness
* no severe central system diseases such as brain infarction
* between 18 and 80
* no liver or kidney dysfunction
* will perform endoscopy for various reasons

Exclusion Criteria

* illiteracy
* color blindness
* can't write or refused to sign informed consent
* unable to follow up regularly or cooperate with the examination
* drug or alcohol abuse
* hearing or visual serious impairment
* has severe central nervous system diseases such as shoke ,neurosyphilis
* uncontrolled high blood pressure or hyperglycemia
* neurosyphilis
* history of craniotomy for various reasons
* liver and kidney dysfunction
* non-digestive tumors
* history of intravenous or general anesthesia for other causes in the last 3 months

Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes