Study on the Value of Three-dimensional Speckle Tracking Technique

NCT ID: NCT03905200

Last Updated: 2019-04-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-03-01

Study Completion Date

2020-12-31

Brief Summary

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For a long time, it has been hoped that doctors could screen and diagnosis of coronary heart disease through non-invasive imaging techniques, so as to maximize the benefit/risk ratio of patients. This trial is to explore the screening and diagnostic value of three-dimensional speckle tracking technology for coronary heart disease, and the evaluation value of 3D speckle track image(3D-STI) technology for cardiac function improvement after coronary intervention, and to seek reliable, accurate and quantifiable non-invasive imaging examination for the diagnosis, follow-up and prognosis of coronary heart disease.

In this study, coronary angiography is taken as the "gold standard", and 3d-STI echocardiography technology is proposed to combine with clinical characteristics of subjects for joint diagnosis, so as to evaluate the value of 3d-sti technology in the diagnosis of coronary heart disease.

Patients were followed up with echocardiography after interventional treatment to explore the feasibility of 3D-STI technology in evaluating cardiac function improvement.

Detailed Description

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Conditions

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Echocardiography, Three-Dimensional Coronary Artery Disease

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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coronary artery disease

Patients who were diagnosed with coronary heart disease at admission and planned to undergo coronary angiography

3D-speckle tracking imaging

Intervention Type DIAGNOSTIC_TEST

The strain peak value and strain peaking time of each segment (including 16 segments) of the left ventricular myocardium can be obtained by 3d-sti technology.

Interventions

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3D-speckle tracking imaging

The strain peak value and strain peaking time of each segment (including 16 segments) of the left ventricular myocardium can be obtained by 3d-sti technology.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* patients diagnosed with coronary heart disease
* patients underwent coronary angiography with or without PCI

Exclusion Criteria

* patients with non-sinus rhythm
* patients with severe heart valvular disease
* patients with severe cardiomyopathy
* patients with congenital heart disease
* patients with severe heart failure stage
* patients with acute myocardial infarction occurred during follow-up
* patients with other extremely severe illness
* patients whose images are not clear enough to mark the endocardium
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Beijing Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Fang Wang

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Beijing Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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Xin Wang, Dotoral

Role: primary

86 10 58115037

References

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Guo Y, Cai YH, Xu T, Song XY, Guo HX, Dong M, Ni D, Li H, Wang F, Xue WF. Echocardiographic video-driven multi-task learning model for coronary artery disease diagnosis and severity grading. Front Bioeng Biotechnol. 2025 Jul 25;13:1556748. doi: 10.3389/fbioe.2025.1556748. eCollection 2025.

Reference Type DERIVED
PMID: 40787200 (View on PubMed)

Guo Y, Xia C, Zhong Y, Wei Y, Zhu H, Ma J, Li G, Meng X, Yang C, Wang X, Wang F. Machine learning-enhanced echocardiography for screening coronary artery disease. Biomed Eng Online. 2023 May 11;22(1):44. doi: 10.1186/s12938-023-01106-x.

Reference Type DERIVED
PMID: 37170232 (View on PubMed)

Guo Y, Wang X, Yang CG, Meng XY, Li Y, Xia CX, Xu T, Weng SX, Zhong Y, Zhang RS, Wang F. Noninvasive assessment of myocardial work during left ventricular isovolumic relaxation in patients with diastolic dysfunction. BMC Cardiovasc Disord. 2023 Mar 10;23(1):129. doi: 10.1186/s12872-023-03156-4.

Reference Type DERIVED
PMID: 36899310 (View on PubMed)

Other Identifiers

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Z161100000516053

Identifier Type: -

Identifier Source: org_study_id

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