Early Detection of Cardiac Damage by Two-Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy
NCT ID: NCT04443400
Last Updated: 2020-06-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
100 participants
OBSERVATIONAL
2020-01-01
2021-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* will receive radiotherapy
* with cardiac exposure during the radiotherapy process
* could receive regular follow-up for 12 months
* written informed consent
Exclusion Criteria
* moderate or severe valvular disease
* cardiomyopathy
* congenital heart disease
* refractory hypertension
* coronary artery disease\*
* heart failure
* arrhythmia requiring intervention
* pericarditis
* acute myocarditis
* participating in other clinical studies of drug intervention
* severe liver and kidney dysfunction
* autoimmune disease
* pulmonary hypertension
coronary artery disease: at least 50% stenosis besed on previous coronary angiography or CTA, or with a history of percutaneous coronary stent implantation.
\*: with LVEF\<50%, unstable anginaļ¼or acute myocardial infarction within 3 months.
ALL
No
Sponsors
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Peking University Third Hospital
OTHER
Responsible Party
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Principal Investigators
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Dan Zhu
Role: STUDY_DIRECTOR
Peking University Third Hospital
Locations
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Peking University Third Hospital
Beijing, Beijing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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References
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Li T, Zhuang H, Wang Y, Li J, Zhu D, Cui M. Two-dimensional speckle tracking echocardiography in evaluating radiation-induced heart damage. Asia Pac J Oncol Nurs. 2021 Dec 25;9(2):119-124. doi: 10.1016/j.apjon.2021.12.008. eCollection 2022 Feb.
Zhu D, Li T, Zhuang H, Cui M. Early Detection of Cardiac Damage by Two-Dimensional Speckle Tracking Echocardiography After Thoracic Radiation Therapy: Study Protocol for a Prospective Cohort Study. Front Cardiovasc Med. 2022 Jan 26;8:735265. doi: 10.3389/fcvm.2021.735265. eCollection 2021.
Other Identifiers
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PekingUTN
Identifier Type: -
Identifier Source: org_study_id
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