Reliability of Echocardiography From Subcostal View

NCT ID: NCT04494152

Last Updated: 2020-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-20

Study Completion Date

2021-10-31

Brief Summary

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The purpose of this study is to assess reliability of echocardiographic assessment of ventricular dimensions and function from subcostal view.

Detailed Description

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Assessment of the function and dimensions of the right and left ventricles is a key part of Point-of-Care ultrasound in critically ill patients. According to the recent guidelines, this evaluation is performed from apical and parasternal views. However, these views may not be clearly visible in the clinical setting of critical illness and subcostal view is often preferred for its higher feasibility. Before clinical adoption, it is necessary to assess whether the isolated examination from subcostal view is reliable enough in the detection of the impairment of systolic function and the size of both ventricles and the investigators decided to evaluate this issue.

Transverse and longitudinal dimensions and function of both ventricles will be measured calculated by transthoracic echocardiography in critically ill patients in the intensive care unit from parasternal and apical views following the recent guidelines. Systolic function of the left ventricle will be expressed by the left ventricular ejection fraction (calculated by biplane method of disc summation) and by the fraction shortening. Systolic function of the right ventricle will be assessed by the tricuspid annular plane systolic excursion, fractional area change, tricuspid lateral annular systolic velocity, and right ventricular index of myocardial performance. From subcostal view, transverse dimensions of both ventricles and novel parameters of systolic function (subcostal tricuspid annular plane systolic excursion, right ventricular subcostal fraction shortening, right ventricular modified subcostal fraction shortening, left ventricular subcostal fraction shortening and left ventricular modified fraction shortening) will be measured.

Then, the reliability of parameters measured in subcostal view will be tested by comparison with conventional parameters taken from apical and parasternal view by correlation analysis and diagnostic test evaluation. The most reliable thresholds of parameters from subcostal view will be calculated by receiver operating characteristic analysis.

Conditions

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Transthoracic Echocardiography

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Critically ill patients

Adult critically ill patients hospitalised in the intensive care unit.

Transthoracic echocardiography

Intervention Type DIAGNOSTIC_TEST

Standard Point-of-Care echocardiographic examination in the intensive care unit.

Interventions

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Transthoracic echocardiography

Standard Point-of-Care echocardiographic examination in the intensive care unit.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Inpatients
* All patients hospitalised in intensive care unit indicated for transthoracic echocardiography examination

Exclusion Criteria

* Age \<18 years
* Insufficient imaging quality of transthoracic echocardiography
* Refusal of echocardiographic examination by patient
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Masaryk Hospital Usti nad Labem

OTHER

Sponsor Role collaborator

Emergency Medical Service of the Central Bohemian Region, Czech Republic

OTHER

Sponsor Role lead

Responsible Party

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Roman Skulec

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Roman Skulec, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Masaryk Hospital Usti nad Labem

Locations

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Masaryk Hospital Usti nad Labem

Ústí nad Labem, , Czechia

Site Status RECRUITING

Countries

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Czechia

Central Contacts

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Roman Skulec, MD, PhD

Role: CONTACT

00420777577497

Barbora Pakostova, MD

Role: CONTACT

00420720172670

Facility Contacts

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Roman Skulec, MD, PhD

Role: primary

00420777577497

References

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Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L, Flachskampf FA, Foster E, Goldstein SA, Kuznetsova T, Lancellotti P, Muraru D, Picard MH, Rietzschel ER, Rudski L, Spencer KT, Tsang W, Voigt JU. Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr. 2015 Jan;28(1):1-39.e14. doi: 10.1016/j.echo.2014.10.003.

Reference Type BACKGROUND
PMID: 25559473 (View on PubMed)

Other Identifiers

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02/2020

Identifier Type: -

Identifier Source: org_study_id

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