Inhomogeneous Ventilation in Adult Post-neurosurgical Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-04-01

Study Completion Date

2019-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Inhomogeneous ventilation was more likely to happen in patients after general anesthesia. Inhomogeneous ventilation may associate with ventilator-induced lung injury. A large number of post-neurosurgical patients was delayed extubation and received mechanical ventilation, so that, inhomogeneous ventilation was more likely to happen in the population. Electrical impedance tomography (EIT) is an noninvasive, radiation-free, high temporal resolution, relatively cheap technique in monitoring ventilation distribution bedside. The investigators aimed to investigate the incidence of inhomogeneous ventilation and factors associated with inhomogeneous ventilation in post-neurosurgical patients under mechanical ventilation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Evaluation of Postoperative Ventilation Distribution With Electrical Impedance Tomography

NCT05389735

Electrical Impedance Tomography

UNKNOWN

Electrical Impedance Tomography in Evaluating the Effects of Noninvasive Ventilation in Post-Operative Cardiac Surgery

NCT03371628

Thoracic Surgery

UNKNOWN NA

The Clinical Application of EIT in Clinically Ill Patients: a Cross-sectional Study

NCT06954415

Electrical Impedance Tomography (EIT)

NOT_YET_RECRUITING

The Effect of Lateral Tilt on Ventilation Distribution in Lungs Assessed by Electrical Impedance Tomography

NCT04235231

Lung Collapse

COMPLETED NA

EIT in Patient Ventilator Asynchrony

NCT04442815

ARDS, Human

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Inhomogeneous ventilation was more likely to happen in patients after general anesthesia. Inhomogeneous ventilation may associate with ventilator-induced lung injury since the gravity-depend collapse and over-distention of nondependent regional in patients under mechanical ventilation. A large number of post-neurosurgical patients was delayed extubation and received mechanical ventilation, so that, inhomogeneous ventilation was more likely to happen in the population. Up to now, there is no research reported about the prevalence of inhomogeneous ventilation and the factors associated with inhomogeneous ventilation in post-neurosurgical patients, in present study, The investigators prospectively enrolled adult patients after neurosurgical operations. Electrical impedance tomography (EIT) is an noninvasive, radiation-free, high temporal resolution, relatively cheap technique in monitoring ventilation distribution bedside. The investigators aimed to investigate the incidence of inhomogeneous ventilation and factors associated with inhomogeneous ventilation in post-neurosurgical patients under mechanical ventilation.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mechanical Ventilation Electrical Impedance Tomography Inhomogeneous Ventilation Neurosurgery

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Undergoing elective neurosurgery operation
* Trachea intubated and mechanical ventilated

Exclusion Criteria

* Age under 18 years-old
* Unstable hemodynamics patients (mean arterial pressure under 65mmHg) after pharmacotherapy
* History of chronic obstructive pulmonary disease(COPD) or asthma
* Contraindication of using EIT (pacemaker, defibrillator, and implantable pumps)
* Unable to install EIT belt (skin infection, wound)
* Incompleteness of thorax (e.g. pneumothorax, rib fracture and etc.) or malformation of thorax.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No