Characterization of Manual Dexterity by Finger Force Manipuladum (FFM) in Patients With Writer's Cramp and in Control Subjects

NCT ID: NCT03797638

Last Updated: 2021-06-22

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2018-10-01
• Study Completion Date: 2019-07-19

Brief Summary

Writer's cramp is a focal dystonia characterized by abnormal movements and postures during writing. Limited finger independence during writing manifests as difficulty suppressing unwanted activations of neighbouring non task-relevant fingers. Patients with Writer's cramp also have difficulty in fine control of grip force.

The investigators have recently developed the Finger Force Manipulandum which quantifies the forces applied by each fingers in different tasks. This method is sensitive for detection and quantification of small unwanted contractions in non-active ('stationary') fingers. Different tasks have been developed to assess abilities such as finger individuation but also fine finger force control, finger movement regularity and speed.

The aim of this study is to assess if developed tasks allow to precisely characterize writer's cramp condition in terms of abilities aforementioned.

To do so, performance of 20 writer's cramp patients in the developed task will be compared with performance of 20 control participants (matched in age, sex and writing hand) in the same tasks.

Conditions

Dystonic Disorder; Focal Dystonia; Writer's Cramp

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: NONE

Study Groups

Patients with writer's cramp

Patients with writer's cramp

Group Type: EXPERIMENTAL

Finger Force Manipuladum (FFM)

Intervention Type: DEVICE

Tasks performed with the device Finger Force Manipuladum (FFM), to assess abilities such as finger individuation but also fine finger force control, finger movement regularity and speed.

Control subjects

Control subjects, without writer's cramp, matched with case subjects with age, gender and hand writing

Group Type: OTHER

Finger Force Manipuladum (FFM)

Intervention Type: DEVICE

Tasks performed with the device Finger Force Manipuladum (FFM), to assess abilities such as finger individuation but also fine finger force control, finger movement regularity and speed.

Interventions

Finger Force Manipuladum (FFM)

Tasks performed with the device Finger Force Manipuladum (FFM), to assess abilities such as finger individuation but also fine finger force control, finger movement regularity and speed.

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Patient with writer's cramp and writing speed <140 letters / min
• Writer's cramp focal dystonia specific to the task of writing
• Patient treated or not with botulinum toxin injection
• Person having attended school in French

• Patients whose writer's cramp has no impact on the handwriting and has kept a writing speed> 140 letters per minute.
• Tremor of writing
• Neurological condition other than writer's cramp (eg Parkinson's syndrome)
• Pain, trauma or pathology of the upper limb of the writing member other than the writer's cramp who required medical or surgical treatment in the last 6 months preceding the initial check-up

•> 18 years old

• Without writer's cramp
• Person having attended school in French

• Tremor of writing
• Neurological condition other than writer's cramp (eg Parkinson's syndrome)
• Pain, trauma or pathology of the upper limb of the writing member other than the writer's cramp who required medical or surgical treatment in the last 6 months preceding the initial check-up

Matching criteria between cases and control patients

• Age (± 5 years)
• Gender
• Hand writing

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Institut National de la Santé Et de la Recherche Médicale, France

OTHER_GOV

Sponsor Role: collaborator

Fondation Ophtalmologique Adolphe de Rothschild

NETWORK

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Jean-Pierre BLETON, PhD

Role: PRINCIPAL_INVESTIGATOR

Fondation A. de Rothschild

Locations

Fondation A de Rothschild

Paris, , France

Countries

France

Other Identifiers

SSA_2018_4

Identifier Type: -

Identifier Source: org_study_id