Effect of Blood Flow Restriction Training Exercises on Hand Grip Strength in Hemiparetic Cerebral Palsied Children

NCT ID: NCT07347795

Last Updated: 2026-02-04

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 40 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2026-02-20
• Study Completion Date: 2026-06-01

Brief Summary

The study aims to investigate the effect of blood flow restriction (BFR) training exercises on the hand grip strength of children with hemiparetic cerebral palsy. Hand grip strength is a vital component of motor function and is often severely compromised in children with hemiparetic CP, which can significantly impact their daily activities and quality of life. Blood flow restriction (BFR) training is a novel exercise technique where a cuff or band is used to partially occlude blood flow during low-intensity resistance exercises. This method has been shown to stimulate muscle growth and strength gains similar to those achieved through high-intensity strength training, without the need for high loads. Given the unique physiological challenges faced by children with hemiparetic CP, BFR training could provide an effective alternative to traditional strength training methods.

Conditions

Cerebral Palsy Spastic Hemiplegic

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Control group

The control group performs traditional hand grip strengthening exercises, focusing on similar exercises but without blood flow restriction. Both groups participate in a similar frequency and duration of training, with a gradual increase in repetitions over the 8 weeks

Group Type: ACTIVE_COMPARATOR

control group

Intervention Type: BEHAVIORAL

The control group performs traditional hand grip strengthening exercises, focusing on similar exercises but without blood flow restriction. Both groups participate in a similar frequency and duration of training, with a gradual increase in repetitions over the 8 weeks.

Study group

Group Type: EXPERIMENTAL

Blood Flow Restriction Training Exercises group

Intervention Type: DEVICE

The BFR group underwent BFR training for 8 weeks, with sessions held three times per week. A tourniquet-style cuff is placed on the upper arm to restrict blood flow during exercise. The exercises involved are low-intensity grip strengthening activities (e.g., squeezing a rubber ball, gripping a hand dynamometer) at 20% of their one-repetition maximum (1RM). The cuff pressure is set at 50-70% of the participants' limb occlusion pressure, as determined by an initial assessment.

Interventions

Blood Flow Restriction Training Exercises group

The BFR group underwent BFR training for 8 weeks, with sessions held three times per week. A tourniquet-style cuff is placed on the upper arm to restrict blood flow during exercise. The exercises involved are low-intensity grip strengthening activities (e.g., squeezing a rubber ball, gripping a hand dynamometer) at 20% of their one-repetition maximum (1RM). The cuff pressure is set at 50-70% of the participants' limb occlusion pressure, as determined by an initial assessment.

Intervention Type: DEVICE

control group

The control group performs traditional hand grip strengthening exercises, focusing on similar exercises but without blood flow restriction. Both groups participate in a similar frequency and duration of training, with a gradual increase in repetitions over the 8 weeks.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

Age will range from 6-12 years

• Diagnosed with hemiparetic cerebral palsy (right or left side).
• According to Modified Ashwer scale, has grade 1 or 1+ grade
• Children with the ability to understand and follow verbal commands and instructions used during training and tests

Exclusion Criteria

• Any contraindications to exercise, such as moderate or severe spasticity, orthopedic deformities, or other serious health conditions.

• Minimum Eligible Age: 6 Years
• Maximum Eligible Age: 12 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Reham Saeed Alsakhawi

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Cairo Universit

Giza, , Egypt

Countries

Egypt

Central Contacts

Alsakhawi

Role: CONTACT

rsm211_pt@yahoo.com

00966504182628

Facility Contacts

Cairo university Cairo university

Role: primary

rsm211_pt@cu.edu.eg

00201015447798

Other Identifiers

P.T.REC/012/005952

Identifier Type: -

Identifier Source: org_study_id