Effects of Partial Sleep Deprivation on Cognitive Function of Anesthesiologists

NCT ID: NCT03784560

Last Updated: 2019-12-03

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 50 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2019-01-02
• Study Completion Date: 2019-06-28

Brief Summary

The purpose of this study was to evaluate differences in cognitive functions at baseline and following night shift at a trauma center among faculty anesthesiologists.

Detailed Description

Anesthesiology is one of the few health-care professions that often demands split-second decisions. This is especially true in a trauma setting where the situation in the operating room can change drastically in a few seconds. Anesthesiologists who cover trauma calls overnight are subject to long work shifts and demanding schedules that may adversely affect their performance. In combination with the disruption of circadian rhythm that can occur with night shift work, decline in performance from the long work shifts can lead to errors in judgment.

An anonymous questionnaire included two groups of different items were used. Items of the first group are about the personal data i.e. age, sex, marital status and parenting status, consumption behavior (tea, coffee, carbonated drinks, tobacco, anxiolytics, antidepressants, psychotropic agents and sport), and professional activity (number of extended worked shifts per month, number of weekends worked per month).

Items of the second group are related to the night shift itself i.e. number of cases, and the rest hours during the shift.

Psychomotor Vigilance Task, Karolinska Sleepiness Scale, Epworth Sleepiness Scale and Trail Making Test before and after the shift were performed.

Conditions

Cognitive Dysfunction; Sleep Deprivation

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

study group

anesthesia residents with 24 hours working shift

The Psychomotor Vigilance Task (PVT)

Intervention Type: OTHER

PVT has emerged as one of the most widely used tools to assess vigilant attention. Vigilance can be defined as sustained attention and tonic alertness. In sleep deprived individuals, vigilance is the component of cognition that is most consistently and dramatically affected. The PVT is a reaction-time test that allows the collection of a large amount of data in a relatively short period of time. These characteristics increase the sensitivity of the test to detect even small changes in vigilant attention, which can wax and wane within seconds.

Epworth Sleepiness Scale

Intervention Type: OTHER

Epworth Sleepiness Scale a set of questions that assess excessive daytime sleepiness during professional activities and vacations.

This scale was designed to assess the efficiency of sleep apnea treatments. It is also used for the subjective sleepiness assessment based on the likelihood of falling asleep in different everyday life situations. This results in an overall score.

Karolinska sleeping scale

Intervention Type: OTHER

The KSS is assumed to be an ordinal scale with a unitary structure. KSS scores may require standardization to control for differences between subjects. The changes observed in the EEG/EOG with drowsiness do not usually appear until KSS scores reach 7 and higher. Lower KSS scores (<5) may reflect differences in the subjective awareness of fatigue as much, or more than, levels of drowsiness.

Higher KSS scores (7+) may refer more specifically to the state of drowsiness because the subject may then have experienced involuntary dozing behavior, with "lapsing" episodes and brief loss of awareness of the here-and-now, followed by arousal and the return of awareness, including some awareness of recently having dozed off

Trail making test

Intervention Type: OTHER

Most variants of this test, which was apparently introduced in 1938 by Partington (Partington \& Leiter, 1949), have at least two conditions. In condition A the participant is to draw lines to connect circled numbers in a numerical sequence (i.e., 1-2-3, etc.) as rapidly as possible. In condition B the participant is to draw lines to connect circled numbers and letters in an alternating numeric and alphabetic sequence (i.e., 1-A-2-B, etc.) as rapidly as possible.

Interventions

The Psychomotor Vigilance Task (PVT)

PVT has emerged as one of the most widely used tools to assess vigilant attention. Vigilance can be defined as sustained attention and tonic alertness. In sleep deprived individuals, vigilance is the component of cognition that is most consistently and dramatically affected. The PVT is a reaction-time test that allows the collection of a large amount of data in a relatively short period of time. These characteristics increase the sensitivity of the test to detect even small changes in vigilant attention, which can wax and wane within seconds.

Intervention Type: OTHER

Epworth Sleepiness Scale

Epworth Sleepiness Scale a set of questions that assess excessive daytime sleepiness during professional activities and vacations.

This scale was designed to assess the efficiency of sleep apnea treatments. It is also used for the subjective sleepiness assessment based on the likelihood of falling asleep in different everyday life situations. This results in an overall score.

Intervention Type: OTHER

Karolinska sleeping scale

The KSS is assumed to be an ordinal scale with a unitary structure. KSS scores may require standardization to control for differences between subjects. The changes observed in the EEG/EOG with drowsiness do not usually appear until KSS scores reach 7 and higher. Lower KSS scores (<5) may reflect differences in the subjective awareness of fatigue as much, or more than, levels of drowsiness.

Higher KSS scores (7+) may refer more specifically to the state of drowsiness because the subject may then have experienced involuntary dozing behavior, with "lapsing" episodes and brief loss of awareness of the here-and-now, followed by arousal and the return of awareness, including some awareness of recently having dozed off

Intervention Type: OTHER

Trail making test

Most variants of this test, which was apparently introduced in 1938 by Partington (Partington \& Leiter, 1949), have at least two conditions. In condition A the participant is to draw lines to connect circled numbers in a numerical sequence (i.e., 1-2-3, etc.) as rapidly as possible. In condition B the participant is to draw lines to connect circled numbers and letters in an alternating numeric and alphabetic sequence (i.e., 1-A-2-B, etc.) as rapidly as possible.

Intervention Type: OTHER

Other Intervention Names

PVT; ESS; KSS; TMT

Eligibility Criteria

Inclusion Criteria

• Full-time faculty anesthesiologists employed at Kasr El- Ainy Hospital.
• Both genders
• Ages of 25-28 years.
• Varying levels of experience.

Exclusion Criteria

• History of chronic neurological disease.
• History of psychiatric disorders such as:

• Episode of major depression within the past 2 years.
• Lifetime history of schizophrenia.
• Other psychotic illness or bipolar illness.

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Bassant M. Abdelhamid

associate professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Bassant abdelhamid, MD

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

Anesthesia Department

Cairo, , Egypt

Countries

Egypt

Other Identifiers

N-35-2017

Identifier Type: -

Identifier Source: org_study_id