Effect of a Short Nap During the Night Shift of Healthcare Workers on Endothelial Function
NCT ID: NCT05955729
Last Updated: 2026-01-13
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
80 participants
INTERVENTIONAL
2024-02-19
2025-12-22
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
NONE
Study Groups
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Nap group
The experimental group will be allocated to do a 30-min on-duty nap during night work, in a dedicated room between 1 am and 4 am.
On-duty Nap
For 12 weeks, an opportunity for a 30-minute nap during the night shift, between 1 a.m. and 4 a.m., in a quiet room with facilities for lying down.
EndoPAT
The EndoPAT device® measures vascular reactivity after a 5-minute occlusion on one arm.
This device measures changes in vascular tone induced by the endothelium at fingertip level using a pair of plethysmographic sensors. The measurement consists of performing a reference recording for 5 minutes on the 2 arms, then a test arm is chosen to perform an occlusion for 5 minutes while continuing the recording.
Popmeter®
The tool is connected to the caregiver's finger and toe via photodiode sensors. Its simple operation enables reproducible measurement of the propagation speed of the pulse wave in 14 seconds.
Panasonic EW3109
Diastolic and systolic blood pressure measured 3 times in succession using an automatic blood pressure monitor (Panasonic EW3109) in the sitting position on the left arm.
ECG Holter
The Holter takes an ECG during the subject's daily activities at home.
Fasting blood sample
15 ml blood sample (venous sampling) will be taken to measure inflammatory biomarkers (hsCRP, IL-6 TNF-α, IL-1β) and blood markers of endothelial function (NO, CRP, SOD, IL-18).
Pichot fatigue scale
The Pichot fatigue scale is an 8-item questionnaire, with a score above 22 indicating excessive fatigue.
French version of the Recovery Needs Scale (BRD)
BRD questionnaire consists of 11 items coded 0 or 1. A score is calculated for each participant, multiplied by 10 to give a score ranging from 0 to 100. The greater the need for recovery, the higher the score.
The Short-Form 36 (SF-36)
The SF-36 questionnaire is used to assess quality of life. It comprises 8 sub-scores ranging from 0 (minimum quality of life) to 100 (maximum well-being).
Pittsburgh Sleep Quality Index (PSQI)
24-question sleep quality assessment scale, a score \> 5 indicates poor sleep quality
Epworth questionnaire
8-question sleepiness assessment scale, a score above 10 indicates excessive sleepiness
The Karolinska Sleepiness Scale
The Karolinska Sleepiness Scale measures daytime sleepiness on a 9-point scale, based on 5 states and 4 intermediate states that are not verbally indicated.
Actimeter
An actimeter will be worn on the non-dominant wrist, uninterrupted day and night, for 7 consecutive days.
Control group
The control group will be allocated to rest in a dedicated room without napping between 1 am and 4 am.
Control condition (30-min rest)
For 12 weeks, an opportunity for a 30-minute rest during the night shift, between 1 a.m. and 4 a.m., in a quiet room without facilities for lying down or napping.
EndoPAT
The EndoPAT device® measures vascular reactivity after a 5-minute occlusion on one arm.
This device measures changes in vascular tone induced by the endothelium at fingertip level using a pair of plethysmographic sensors. The measurement consists of performing a reference recording for 5 minutes on the 2 arms, then a test arm is chosen to perform an occlusion for 5 minutes while continuing the recording.
Popmeter®
The tool is connected to the caregiver's finger and toe via photodiode sensors. Its simple operation enables reproducible measurement of the propagation speed of the pulse wave in 14 seconds.
Panasonic EW3109
Diastolic and systolic blood pressure measured 3 times in succession using an automatic blood pressure monitor (Panasonic EW3109) in the sitting position on the left arm.
ECG Holter
The Holter takes an ECG during the subject's daily activities at home.
Fasting blood sample
15 ml blood sample (venous sampling) will be taken to measure inflammatory biomarkers (hsCRP, IL-6 TNF-α, IL-1β) and blood markers of endothelial function (NO, CRP, SOD, IL-18).
Pichot fatigue scale
The Pichot fatigue scale is an 8-item questionnaire, with a score above 22 indicating excessive fatigue.
French version of the Recovery Needs Scale (BRD)
BRD questionnaire consists of 11 items coded 0 or 1. A score is calculated for each participant, multiplied by 10 to give a score ranging from 0 to 100. The greater the need for recovery, the higher the score.
The Short-Form 36 (SF-36)
The SF-36 questionnaire is used to assess quality of life. It comprises 8 sub-scores ranging from 0 (minimum quality of life) to 100 (maximum well-being).
Pittsburgh Sleep Quality Index (PSQI)
24-question sleep quality assessment scale, a score \> 5 indicates poor sleep quality
Epworth questionnaire
8-question sleepiness assessment scale, a score above 10 indicates excessive sleepiness
The Karolinska Sleepiness Scale
The Karolinska Sleepiness Scale measures daytime sleepiness on a 9-point scale, based on 5 states and 4 intermediate states that are not verbally indicated.
Actimeter
An actimeter will be worn on the non-dominant wrist, uninterrupted day and night, for 7 consecutive days.
Interventions
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On-duty Nap
For 12 weeks, an opportunity for a 30-minute nap during the night shift, between 1 a.m. and 4 a.m., in a quiet room with facilities for lying down.
Control condition (30-min rest)
For 12 weeks, an opportunity for a 30-minute rest during the night shift, between 1 a.m. and 4 a.m., in a quiet room without facilities for lying down or napping.
EndoPAT
The EndoPAT device® measures vascular reactivity after a 5-minute occlusion on one arm.
This device measures changes in vascular tone induced by the endothelium at fingertip level using a pair of plethysmographic sensors. The measurement consists of performing a reference recording for 5 minutes on the 2 arms, then a test arm is chosen to perform an occlusion for 5 minutes while continuing the recording.
Popmeter®
The tool is connected to the caregiver's finger and toe via photodiode sensors. Its simple operation enables reproducible measurement of the propagation speed of the pulse wave in 14 seconds.
Panasonic EW3109
Diastolic and systolic blood pressure measured 3 times in succession using an automatic blood pressure monitor (Panasonic EW3109) in the sitting position on the left arm.
ECG Holter
The Holter takes an ECG during the subject's daily activities at home.
Fasting blood sample
15 ml blood sample (venous sampling) will be taken to measure inflammatory biomarkers (hsCRP, IL-6 TNF-α, IL-1β) and blood markers of endothelial function (NO, CRP, SOD, IL-18).
Pichot fatigue scale
The Pichot fatigue scale is an 8-item questionnaire, with a score above 22 indicating excessive fatigue.
French version of the Recovery Needs Scale (BRD)
BRD questionnaire consists of 11 items coded 0 or 1. A score is calculated for each participant, multiplied by 10 to give a score ranging from 0 to 100. The greater the need for recovery, the higher the score.
The Short-Form 36 (SF-36)
The SF-36 questionnaire is used to assess quality of life. It comprises 8 sub-scores ranging from 0 (minimum quality of life) to 100 (maximum well-being).
Pittsburgh Sleep Quality Index (PSQI)
24-question sleep quality assessment scale, a score \> 5 indicates poor sleep quality
Epworth questionnaire
8-question sleepiness assessment scale, a score above 10 indicates excessive sleepiness
The Karolinska Sleepiness Scale
The Karolinska Sleepiness Scale measures daytime sleepiness on a 9-point scale, based on 5 states and 4 intermediate states that are not verbally indicated.
Actimeter
An actimeter will be worn on the non-dominant wrist, uninterrupted day and night, for 7 consecutive days.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Be aAged between 18 and 65
* Working at least 80% of a full-time equivalent post
* Working 12-hour shifts (day/night) in continuous care services
* Being affiliated or entitled under a social security scheme
* Havinge received informed information about the study and have co-signed, with the investigator, a consent to participate in the study
Exclusion Criteria
* Have a mMedically diagnosed sleep disorder such asof the hypersomnia or insomnia type
* Have a diagnosed and treated mental pathology
* Usually take a nap in the workplace in a quiet room
* Be pregnant or breastfeeding
* Have medically diagnosed neurovascular or neuromuscular pathologies
18 Years
65 Years
ALL
Yes
Sponsors
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Centre Hospitalier Universitaire de Saint Etienne
OTHER
Responsible Party
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Principal Investigators
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Frédéric ROCHE, MD PhD
Role: PRINCIPAL_INVESTIGATOR
Centre Hospitalier Universitaire de Saint Etienne
Locations
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Chu de Saint-Etienne
Saint-Etienne, , France
Countries
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Other Identifiers
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2023-A01109-36
Identifier Type: OTHER
Identifier Source: secondary_id
23CH138
Identifier Type: -
Identifier Source: org_study_id
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