ACL Versus ALL + ACL Study

NCT ID: NCT03740022

Last Updated: 2024-11-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

592 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-02

Study Completion Date

2024-06-10

Brief Summary

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The aim of the study is to show a reduction of a re-rupture rate with an ACL (antero crusader ligament) + ALL (anterolateral ligament) combined technique compared to a classical Kenneth-Jones ACL (antero crusader ligament) reconstruction technique.

Detailed Description

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The aim is to evaluate the rate of re-rupture and to analyze knee function through scores analysis as International Knee Documentation Committee Subjective Knee (IKDC), Knee injury and osteoarthritis outcome score (KOOS), Lysholm-Tegner, and by objective measurements of laximetry and rotation.

This study should include 2 groups of 296 patients with isolated ACL (antero crusader ligament) with clinical rotation :

* operated by a conventional patellar tendon technique (first group)
* operated by a technique combining a ALL (anterolateral ligament) and ACL plasty for the second group

Conditions

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Anterior Cruciate Ligament Injury Ligament Rupture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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ACL plasty

The surgical procedure consists of a ligamentoplasty of the antero crusader ligament (ACL) with the patellar tendon according to a conventional arthroscopic procedure.

Group Type ACTIVE_COMPARATOR

ACL plasty

Intervention Type PROCEDURE

standard ligamentoplasty by Kenneth Jones

ACL + ALL plasty

The surgical procedure consists of a hamstring ligamentoplasty (DIDT) of the antero crusader ligament (ACL) and anterolateral ligament (ALL) according to a published arthroscopic procedure.

Group Type EXPERIMENTAL

ACL + ALL plasty

Intervention Type PROCEDURE

standard ligamentoplasty and anterolateral plasty

Interventions

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ACL plasty

standard ligamentoplasty by Kenneth Jones

Intervention Type PROCEDURE

ACL + ALL plasty

standard ligamentoplasty and anterolateral plasty

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients with total isolated antero crusader ligament (ACL) rupture who are candidates for surgical reconstruction
* Patients between 18 and 35 years old
* Patients with weekly sporting activities
* Patients with chronic rotatory instability with a positive pivot shift
* Patients who have been informed and do not object the research

Exclusion Criteria

* Patients with multi-ligament knee involvement
* Patients under 18 years old or over 35 years old
* Patients with a BMI of under 18.5 or over 30
* Patients with any contraindication to general anaesthesia
* Professional sportsmen/women
* Patients with congenital malformation or a rheumatic disease
* Patients with repeated antero crusader ligament (ACL) rupture
* Patients with serious ligament disease in the contralateral knee
* Patients who refuse to take part in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ramsay Générale de Santé

OTHER

Sponsor Role collaborator

Ascopharm Groupe Novasco

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hôpital Privé Jean Mermoz - Centre Paul Santy

Lyon, , France

Site Status

Countries

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France

References

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Sonnery-Cottet B, Pioger C, Vieira TD, Franck F, Kajetanek C, Fayard JM, Thaunat M, Saithna A. Combined ACL and Anterolateral Reconstruction Is Not Associated With a Higher Risk of Adverse Outcomes: Preliminary Results From the SANTI Randomized Controlled Trial. Orthop J Sports Med. 2020 May 1;8(5):2325967120918490. doi: 10.1177/2325967120918490. eCollection 2020 May.

Reference Type DERIVED
PMID: 32490026 (View on PubMed)

Other Identifiers

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2016-A00144-47

Identifier Type: -

Identifier Source: org_study_id

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