Safety and Efficacy of the Knee-T-nol Anterior Cruciate Ligament (ACL) Prosthesis

NCT ID: NCT01450332

Last Updated: 2011-10-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-03-31

Study Completion Date

2013-01-31

Brief Summary

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The study is designed to evaluate the safety and efficacy of implanting the Tavor ACL prosthesis in patients with a ruptured ACL by improvement of healing kinetics as well as major adverse treatment events (AEs). it is designed to test the hypothesis that there is a difference in healing kinetics of ACL deficient knees treated by ACL reconstruction using autografts and those in which such procedure was performed with the Tavor prosthesis.

Detailed Description

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Conditions

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Anterior Cruciate Ligament Rupture

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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study

Group Type EXPERIMENTAL

Knee-T-Nol

Intervention Type DEVICE

The ACL prosthesis is intended for the treatment of ruptured ACL. It will be used as an implant to replace the native, torn ACL. Implantation will be done using arthroscopy

Interventions

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Knee-T-Nol

The ACL prosthesis is intended for the treatment of ruptured ACL. It will be used as an implant to replace the native, torn ACL. Implantation will be done using arthroscopy

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Patient is \>= 18 years old
2. Patient has a ruptured ACL
3. Operated knee has full range of motion and no swelling
4. Patient understands the study requirements and the treatment procedures and rehabilitation and provides written Informed Consent before any study-specific tests or procedures are performed.
5. The patient commits to fully undergo the rehabilitation program and return for the scheduled post-operative follow-up visits at the clinic.

Exclusion Criteria

1. Skeletal immaturity
2. Pregnancy
3. Patient with:

* Uncontrolled systemic hypertension
* Severe uncontrolled Diabetes Mellitus
* Epiphyses That Have Not Yet Closed
* Periarticular or Patella Fracture
* History of Metabolic Bone Disease (e.g.., Osteoporosis, Rickets)
* Crystal deposition disease, e.g., gout
* Inflammatory joint disease, e.g., rheumatoid arthritis
* Severe degenerative joint disease
* Known neoplastic disease
* HIV positive
* Current steroid therapy in excess of prednisone 5 mg/day
* Other severe, life-threatening systemic disease or any medical condition that interferes with their ability to participate in a rehabilitation program
4. The subject has participated in, or is planned to participate in, any investigational drug or device study within the past 30 days and for the duration of this study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tavor Ltd.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Idan M Tobis, B.Sc.

Role: STUDY_DIRECTOR

Tavor Ltd.

Yoram Litwin, MD

Role: PRINCIPAL_INVESTIGATOR

Shaare Zedek Medical Center

Locations

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Shhare Zedek Medical Center

Jerusalem, Israel, Israel

Site Status RECRUITING

Countries

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Israel

Central Contacts

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Jonathan S Yalom, B.Sc.

Role: CONTACT

+972-9-7733910

Idan M Tobis, B.Sc.

Role: CONTACT

+972-52-6337098

Other Identifiers

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TACLPPS01 Rev 4

Identifier Type: -

Identifier Source: org_study_id