Study of Meniscal Allografts

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-09-30

Study Completion Date

2019-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Total or subtotal meniscectomies in young patients are currently responsible of pain and limitation of activities. There isn't any other treatment than meniscal replacement. But there is no randomized clinical trial on meniscal allograft to validate the efficiency of this treatment.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Long Term Outcomes of Osteochondral Allografts for Osteochondral Defects of the Knee

NCT02308358

Outcomes of Allograft

WITHDRAWN

Autologous Chondrocyte Implantation in the Patellofemoral Joint

NCT00212849

Chondrosis Patellar Articular Cartilage Lesions Trochlear Articular Cartilage Lesions

COMPLETED

The Benefit of Arthroscopic Partial Meniscectomy in Middle-Aged Patients

NCT01264991

Degenerative Meniscus Tear

TERMINATED NA

Study Protocol to Evaluate Clinical and Imaging Results of Knee Fresh Osteochondral Allografts

NCT04236492

Osteochondral Defect

RECRUITING

Clinical Effect of Allogeneic Meniscus Transplantation

NCT04960436

Meniscus Lesion

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Meniscal allograft is done through United States and Europe since the last fifteen years. Operative technique has regularly improved, especially because of new arthroscopic devices. The meniscal allografts to be used are taken from dead donors and then frozen according to all the reglementary aspects of tissue bank.

The graft has to be ordered as soon as the patient is randomized ; the sizing of the graft ordered is important depending on the gender size and height of the patient and on the measures of the tibial plateau on X Rays.

The arthroscopic procedure is done under general or loco-regional anesthesia. The graft has to be prepared with bone blocks attached to the anterior and posterior horn of the meniscal graft. These bone blocks will be fixed through bone tunnels and the meniscus itself will be sutured on the peripheral meniscus synovial rim.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Meniscectomy Sequelae

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Meniscal Allograft

Group Type EXPERIMENTAL

Meniscal Allograft

Intervention Type PROCEDURE

Meniscal Allograft

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Meniscal Allograft

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age from 18 on
* Previous total or subtotal meniscectomy
* Medical insurance
* Female patients have to be under contraceptive treatment
* Sign consent form

Exclusion Criteria

* Age \< 18 years
* Pregnant or breast-feeding woman
* Need of a simultaneous frontal osteotomy
* Inflammatory disease
* Septic background
* Psychiatric background
* Understanding difficulties or problems for follow-up
* No consent
* No medical insurance

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No