Ceramic Tooth Restorations - a Comparison Study

NCT ID: NCT03517124

Last Updated: 2018-05-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-01-05

Study Completion Date

2020-12-31

Brief Summary

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This randomized clinical study aims to compare success and survival of two different ceramic tooth restoration materials. The hypothesis for the study is that fluoride treated zirconia will retain as good as lithium disilicate reinforced glass ceramic when cemented by the same resin cement.

One group of patients will receive a restoration in fluoride treated zirconia, the other group will receive a restoration in reinforced glass ceramic. All restorations will be cemented in the same manner. At 3, 6, 12 and 24 months the participants will be examined.

Detailed Description

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A randomized controlled clinical study that aims to compare success and survival of potassium hydrogen difluoride (KHF2) etched zirconium dioxide and lithium disilicate reinforced glass ceramic cemented to molars/premolares using dual cure resin cement.

The null hypothesis for the study is that zirconium dioxide and lithium disilicate reinforced glass ceramic will retain equally good tooth substance when cemented with resin cement.

Participants are recruited from the student clinic at Faculty of Dentistry, University of Oslo. Patients who fulfill the inclusion criteria 1) age above 18, 2) require restoration on premolar/molar and 3) are able to come to treatment and recall, are informed about the study and invited to participate. Consent to participation are signed by the patient. At any time and for any reason participants can withdraw from the study.

Personal information will be registered in Service for Sensitive Data, which is a platform to collect, store, analyze and share sensitive data. An encoded research file will be kept separate from the patient journal.The content of this file will be patient journal number and classification of the restoration on a four level scale (Californian Dental Association - CDA) for each recall.

A randomizing tool will be used to decide which ceramic restoration each participant will receive. Treatment will be performed by one clinician. The tooth preparation will be with little retention, and preferably supragingival. For cementing the restorations a standardized protocol for a dual cure resin cement will be used.

Participants only have to pay for the dental technician expenses and will be the same amount regardless of type of ceramic.

Each participant will be examined at 3, 6, 12 and 24 months by a clinician different from the one who performed the treatment. The 4 level CDA classification will be used to characterise each restoration.

Each of the two treatment groups will consist of 20 participants. Significant results will be achieved with the approximate distribution across categories: Category 1: 19,9 %, category 2: 79,4 %, category 3: 4,6 %, category 4: 2,5 %

Conditions

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Dental Restoration Failure of Marginal Integrity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled clinical study
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Zirconia restorations

Dental restorations in surface modified zirconia bonded to tooth substance by dual cure resin cement

Group Type EXPERIMENTAL

Ceramic tooth restoration

Intervention Type OTHER

Dental restorations

e.max

Restorations in e.max bonded to tooth substance by dual cure resin cement

Group Type ACTIVE_COMPARATOR

Ceramic tooth restoration

Intervention Type OTHER

Dental restorations

Interventions

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Ceramic tooth restoration

Dental restorations

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

18 years or older In the need of treatment on molars or premolars Lives near by Oslo

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Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Nordic Institute of Dental Materials

UNKNOWN

Sponsor Role collaborator

University of Oslo

OTHER

Sponsor Role lead

Responsible Party

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Hans Jacob Rønold

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jan Eirik Ellingsen, Professor

Role: STUDY_CHAIR

Faculty of Dentistry, Institute of Clinical Dentistry

Locations

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Institute of Clinical Dentistry, University of Oslo

Oslo, , Norway

Site Status

Countries

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Norway

References

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Ruyter EI, Vajeeston N, Knarvang T, Kvam K. A novel etching technique for surface treatment of zirconia ceramics to improve adhesion of resin-based luting cements. Acta Biomater Odontol Scand. 2017 Apr 14;3(1):36-46. doi: 10.1080/23337931.2017.1309658. eCollection 2017 Jan.

Reference Type BACKGROUND
PMID: 28642930 (View on PubMed)

Other Identifiers

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2016/957

Identifier Type: -

Identifier Source: org_study_id

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