Anesthetic Cost Analysis With Desflurane in Automated Gas Control Mode

NCT ID: NCT03465475

Last Updated: 2021-08-25

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-07-01
• Study Completion Date: 2021-03-01

Brief Summary

Inhalation agents constitute the major part of anesthetic drug costs (20% - 25%) and a significant portion of the applied inhalation agents are thrown into the atmosphere through the waste gas system without being absorbed by the patient. The amount of waste gas is directly correlated to the fresh gas flow (FGF). Reducing the TGA during general anesthesia reduces the consumption of inhalant agents and contributes to the reduction of greenhouse gas pollution. Risks such as hypoxia, hypercapnia, inadequate depth of anesthesia and potential toxic gas accumulation were associated with low flow anesthesia, but the patient was provided with adequate safety by following pulse oximetry, capnography, FiO2 and anesthetic gas analysis. We aimed to perform anesthetic cost analysis and patient security in automated gas control mode (AGC).

Detailed Description

After the ethical approvel 60 adult patients scheduled for hepatectomy will be taken to study. Patients will be monitored after they are taken to the operating room (ECG, NIBP, SpO2, Body Temp, BIS, NIRS, PVI, PI, ORI). After the anesthesia induction and tarakeal entubation, first twenty patient will take 300 mL fresh gas flow with AGC mode (group 1), Second twenty patient will take 600 mL fresh gas flow with AGC mode (group 2), third twenty patient will take 600 mL fresh gas flow with manually. Hemodynamic and gas consumption data will be recorded. An operating room will be reserved for this study.

Conditions

Safety Issues

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

Group 1

The patient who receive 300 mL fresh gas flow with AGC mode during the general anesthesia

No interventions assigned to this group

Group 2

The patient who receive 600 mL fresh gas flow with AGC mode during the general anesthesia

No interventions assigned to this group

Group 3

The patient who receive 600 mL fresh gas flow with manuelly during the general anesthesia

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Adult patients undergoing hepatectomy with general anesthesia

Exclusion Criteria

• Essential data missing
• Patient participating in other research projects
• Drug allergy
• Anesthetic complication story

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Inonu University

OTHER

Sponsor Role: lead

Responsible Party

Yusuf Ziya ÇOLAK

Assistant Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Yusuf Z Çolak, MD

Role: PRINCIPAL_INVESTIGATOR

Investigator

Locations

Inonu Univercity

Malatya, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

Inonu uni

Identifier Type: -

Identifier Source: org_study_id