Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
106 participants
OBSERVATIONAL
2014-01-31
2014-01-31
Brief Summary
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The objective of this study is to identify time to achieve alveolar concentration of desflurane at1, 2, 3, 4, 5 and 6%.
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Detailed Description
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The objective of this study is to identify time to achieve alveolar concentration of desflurane at 1, 2, 3, 4, 5 and 6% with 1-1-12 wash-in protocol.
All patients will receive iv propofol 2 mg/kg as induction agent and succinyl choline 1.5 mg/kg for intubation. Then the ventilation will be controlled to achieve end-tidal CO2 30-35 mmHg with O2:N2O 1:1 L/min with desflurane 12%. Time to achieve alveolar concentration of desflurane at 1, 2, 3, 4, 5 and 6% will be recorded and analyzed. After that, the concentration of desflurane and anesthetic technique will be adjusted to requirement of anesthesiologist.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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1-1-12 wash-in
wash-in using O2:N2O 1:1 L/min with desflurane 12%
1-1-12 wash-in
wash-in phase during start of low flow anesthesia
Interventions
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1-1-12 wash-in
wash-in phase during start of low flow anesthesia
Eligibility Criteria
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Inclusion Criteria
* age 18-64 years
Exclusion Criteria
* contraindicated for N2O
* with pulmonary or cardiac disease
18 Years
64 Years
ALL
Yes
Sponsors
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Khon Kaen University
OTHER
Responsible Party
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Thepakorn Sathitkarnmanee
Associate Professor
Principal Investigators
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Thepakorn Sathitkarnmanee, MD
Role: PRINCIPAL_INVESTIGATOR
Faculty of Medicine, Khon Kaen University
Locations
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Srinagarind Hospital
Khon Kaen, , Thailand
Countries
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Other Identifiers
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HE561247
Identifier Type: -
Identifier Source: org_study_id
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