Effect of PEEP on Arterial Oxygen Partial Pressure in Elderly Patients With Lithotomy Position Using LMA Supreme™
NCT ID: NCT03390127
Last Updated: 2018-04-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
68 participants
INTERVENTIONAL
2018-01-05
2018-03-21
Brief Summary
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Detailed Description
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In urologic surgery, elderly patients are common. Since aging decreases the elasticity of lung tissues and allowing the collapse of small airways, old age is a risk factor for postoperative atelectasis. Lithotomy position is the preferred position in urologic surgery. However, it causes the abdominal viscera to displace the diaphragm cephalad, reducing lung compliance and resulting atelectasis. Therefore, in elderly patients undergoing urologic surgery with lithotomy position, PEEP may be essential to prevent postoperative atelectasis.
Laryngeal mask airway (LMA) has been widely used in urologic surgery with lithotomy position because of short surgical time and no necessity of administration of muscle relaxant. However, application of PEEP when using LMA is still controversy. Therefore, in the present study, we aimed to compare the effect of PEEP on arterial oxygen partial pressure in elderly patients undergoing urologic surgery using LMA supreme™ in a lithotomy position.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
QUADRUPLE
Study Groups
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Group P
After LMA Supreme™ insertion, PEEP of 7 cmH2O would apply during general anesthesia with mechanical ventilation.
PEEP
After LMA Supreme™ insertion, it's proper position is confirmed. Then, PEEP of 7 cmH2O is applied during mechanical ventilation.
Group Z
After LMA Supreme™ insertion, PEEP would not apply during general anesthesia with mechanical ventilation.
No interventions assigned to this group
Interventions
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PEEP
After LMA Supreme™ insertion, it's proper position is confirmed. Then, PEEP of 7 cmH2O is applied during mechanical ventilation.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Elderly patients (65 ≤ Age \< 80)
* American Society of Anesthesiologists (ASA) physical status: 1-3
* Patients who voluntarily agreed to participate in this clinical study
Exclusion Criteria
* Hemodynamic instability during perioperative period
* Lung diseases (chronic obstructive pulmonary disease, asthma, bullae, pleural effusion)
* Obesity (BMI ≥ 30 kg/m2)
* Neck or upper respiratory tract pathologies
* An increased risk of pulmonary aspiration
* Anticipation of the difficult laryngeal mask fixation due to poor dentition
65 Years
79 Years
ALL
No
Sponsors
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Asan Medical Center
OTHER
Responsible Party
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Young-Kug Kim
Professor
Principal Investigators
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Young-Kug Kim, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Asan Medical Center
Locations
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Asan medical center
Seoul, , South Korea
Countries
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Other Identifiers
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2017-1397
Identifier Type: -
Identifier Source: org_study_id
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