Impact of Sprint Stair Climbing "Snacks" on Markers of Metabolism and Vascular Function

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-10-01

Study Completion Date

2019-08-30

Brief Summary

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Prolonged sitting has been shown to impair metabolism and vascular function. The overall purpose of this study is to determine if breaking up prolonged (9 hours) of sitting with brief (\~20 second) stair climbing exercise "snacks" can improve markers of metabolic control and vascular health in healthy young male participants and in males or females with overweight/obesity who are at risk of insulin resistance. An additional purpose is to determine if saliva insulin can be used as a valid indicator of blood insulin when measured throughout the day in sedentary and active conditions and when diets with different amounts of carbohydrates are consumed.

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Detailed Description

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Conditions

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Physical Activity Diet Modification

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Participants complete three conditions in a repeated crossover design.

Primary Study Purpose

OTHER

Blinding Strategy

NONE

It is not possible to mask the exercise or diet interventions.

Study Groups

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High-Carbohydrate Sedentary

Participants will remain seated for 9 hours (except for using the restroom) while consuming a high-carbohydrate diet (3 meals)

Group Type EXPERIMENTAL

High-Carbohydrate Sedentary

Intervention Type BEHAVIORAL

Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period.

High-Carbohydrate Active

Participants will remain seated for 9 hours (except for using the restroom) while consuming a high-carbohydrate diet (3 meals) but will complete 8 stair climbing sprint "snacks" once per hour involving ascending 3 flights of stairs at a vigorous pace (\~20 seconds each).

Group Type EXPERIMENTAL

High-Carbohydrate Active

Intervention Type BEHAVIORAL

Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period except that once every hour they will ascend three flights of stairs vigorously (stair climbing sprint "snack") for a total of 8 active breaks.

Low-Carbohydrate Sedentary

Participants will remain seated for 9 hours (except for using the restroom) while consuming a low-carbohydrate diet (3 meals)

Group Type ACTIVE_COMPARATOR

Low-carbohydrate Sedentary

Intervention Type BEHAVIORAL

Three low-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period. This condition will provide a condition where the blood glucose and insulin responses are relatively low and stable throughout the day.

Interventions

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High-Carbohydrate Sedentary

Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period.

Intervention Type BEHAVIORAL

High-Carbohydrate Active

Three high-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period except that once every hour they will ascend three flights of stairs vigorously (stair climbing sprint "snack") for a total of 8 active breaks.

Intervention Type BEHAVIORAL

Low-carbohydrate Sedentary

Three low-carbohydrate meals will be consumed (breakfast, lunch, and dinner) at \~3 hour intervals while participants remain in a seated position for the entire 9 hour intervention period. This condition will provide a condition where the blood glucose and insulin responses are relatively low and stable throughout the day.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Non-smoking

Elevated waist circumference (\>102 cm for male and \>88 cm for female)

Exclusion Criteria

Diagnosed with diabetes or prediabetes (fasting blood sugar more than 6.0 mmol/l) or any other chronic condition that may impact glucose or insulin levels.

BMI is over 25 kg/m2 Take medications which may affect glucose and insulin levels Allergic to eggs. Smoker Competitive or serious endurance athlete.

Diagnosed with diabetes (fasting blood sugar more than 7.0 mmol/l) Take medications which may affect glucose and insulin levels Allergic to eggs. Smoker Competitive or serious endurance athlete.

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes